0-dimensional biomaterials show inductive properties.

The extracellular domain of TMEM27 is cleaved in human beta cells.

Podocytes are motile and migrate in the presence of injury.

Inositol lipid 3-phosphatase PTEN converts Ptdlns(3,4)P 2 into phosphatidylinositol 4-phosphate.

Crossover hot spots are not found within gene promoters in Saccharomyces cerevisiae.

Macrolides protect against myocardial infarction.

IFIT1 restricts viral replication by sequestrating mis-capped viral RNAs.

In adult tissue, most T cells are memory T cells.

High levels of copeptin decrease risk of diabetes.

Hypothalamic glutamate neurotransmission is crucial to energy balance.

Low nucleosome occupancy correlates with low methylation levels across species.

Nanoparticles can be targeted against specific cell types by incorporating aptamers into lipid nanoparticles.

Flexible molecules experience greater steric hindrance in the tumor microenviroment than rigid molecules.

Rapid phosphotransfer rates govern fidelity in two component systems

Proteins synthesized at the growth cone are ubiquitinated at a higher rate than proteins from the cell body.

The arm density of TatAd complexes is due to structural rearrangements within Class1 TatAd complexes such as the 'charge zipper mechanism'.

De novo assembly of sequence data has more specific contigs than unassembled sequence data.

All hematopoietic stem cells segregate their chromosomes randomly.

Macropinocytosis contributes to a cell's supply of amino acids via the intracellular uptake of protein.

Gene expression does not vary appreciably across genetically identical cells.


1,000 genomes project enables mapping of genetic sequence variation consisting of rare variants with larger penetrance effects than common variants.

Arginine 90 in p150n is important for interaction with EB1.

The benefits of colchicine were achieved with effective widespread use of secondary prevention strategies such as high-dose statins.

Localization of PIN1 in the Arabidopsis embryo does not require VPS9a

Activator-inhibitor pairs are provided dorsally by Admpchordin.

Combination nicotine replacement therapies with varenicline or bupropion lead to significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

HNF4A mutations can cause diabetes in mutant carriers by the age of 14 years

Localization of PIN1 in the roots of Arabidopsis does not require VPS9a

The PPR MDA5 has two N-terminal CARD domains.

Downregulation and mislocalization of Scribble prevents cell transformation and mammary tumorigenesis.

The amount of publicly available DNA data doubles every 10 years.

Low nucleosome occupancy correlates with low methylation levels across species.

Microarray results from culture-amplified mixtures of serotypes correlate poorly with microarray results from uncultured mixtures.

Functional consequences of genomic alterations due to Myelodysplastic syndrome (MDS) are poorly understood due to the lack of an animal model.

Homozygous deletion of murine Sbds gene from osterix-expressing mesenchymal stem and progenitor cells (MPCs) prevents oxidative stress.

Hematopoietic Stem Cell purification reaches purity rate of up to 50%.

In domesticated populations of Saccharomyces cerevisiae, whole chromosome aneuploidy is very uncommon.

Occupancy of ribosomes by IncRNAs mirror 5 0-UTRs


1/2000 in UK have abnormal PrP positivity.

Cellular aging closely links to an older appearance.

Ly49Q directs the organization of neutrophil migration to inflammation sites by regulating membrane raft functions.

Discrimination between the initiator and elongation tRNAs depends on the translation initiation factor IF3.

Suboptimal nutrition is not predictive of chronic disease

Ly6C hi monocytes have a lower inflammatory capacity than Ly6C lo monocytes.

Fz/PCP-dependent Pk localizes to the anterior membrane of neuroectoderm cells during zebrafish neuralation

The severity of cardiac involvement in amyloidosis can be described by the degree of transmurality of late gadolinium enhancement in MRI.

Functional consequences of genomic alterations due to Myelodysplastic syndrome (MDS) are poorly understood due to the lack of an animal model.

Healthcare delivery efficiency in crowded delivery centers is impaired by improving structural, logistical, and interpersonal elements.

The PRR MDA5 is a sensor of RNA virus infection.

High levels of CRP reduces the risk of exacerbations in chronic obstructive pulmonary disease (COPD).

High-sensitivity cardiac troponin T (HSCT-T) dosage may not be diagnostic if the onset of symptoms occurs less than 3 hours before acute myocardial injury (AMI).

Inositol lipid 3-phosphatase PTEN converts Ptdlns(3,4)P 2 into phosphatidylinositol 4-phosphate.

CX3CR1 on the Th2 cells impairs T cell survival

CX3CR1 on the Th2 cells promotes T cell survival

The PRR MDA5 has a central DExD/H RNA helices domain.

Mice defective for deoxyribonucleic acid (DNA) polymerase I (polI) reveal increased sensitivity to ionizing radiation (IR).


5% of perinatal mortality is due to low birth weight.

S-nitrosylated GAPDH physiologically transnitrosylates histone deacetylases.

Low expression of miR7a does represses target genes and exerts a biological function in ovaries.

Angiotensin converting enzyme inhibitors are associated with increased risk for functional renal insufficiency.

Hypoglycemia increases the risk of dementia.

Pyridostatin destabilizes the G - quadruplex in the telomeric region.

Incidence rates of cervical cancer have decreased.

The YAP1 and TEAD complex tanslocates into the nucleus where it interacts with transcription factors and DNA-binding proteins that modulate target gene transcription.

N-terminal cleavage reduces success identifying transcription start sites.

Transplanted human glial progenitor cells are incapable of forming a neural network with host animals' neurons.

Participating in six months of physical activity improves cognitive functioning.

Birth-weight is positively associated with breast cancer.

Women with a higher birth weight are more likely to develop breast cancer later in life.

Vitamin D deficiency is unrelated to birth weight.

The risk of breast cancer among parous women increases with placental weight of pregnancies, and this association is strongest for premenopausal breast cancer.

Incidence rates of cervical cancer have increased due to nationwide screening programs based primarily on cytology to detect uterine cervical cancer.

Obesity is determined solely by environmental factors.

Incidence of heart failure decreased by 10% in women since 1979.

High cardiopulmonary fitness causes increased mortality rate.


A deficiency of vitamin B12 increases blood levels of homocysteine.

Many proteins in human cells can be post-translationally modified at lysine residues via acetylation.

The availability of safe places to study is effective at decreasing homelessness.

Patients in stable partnerships have a faster progression from HIV to AIDS.

The one-child policy has been successful in lowering population growth.

The benefits of colchicine were achieved with effective widespread use of secondary prevention strategies such as high-dose statins.

IRG1 has antiviral effects against neurotropic viruses.

Homozygous deletion of murine Sbds gene from osterix-expressing mesenchymal stem and progenitor cells (MPCs) prevents oxidative stress.

Cells undergoing methionine restriction may activate miRNAs.

Tirasemtiv has no effect on fast-twitch muscle.

1,000 genomes project enables mapping of genetic sequence variation consisting of rare variants with larger penetrance effects than common variants.

Mutations in G-Beta protein GNB2 are present in many cancers, resulting in loss of interaction with G-alpha subunits and concomitant activation of AKT pathway.

High dietary calcium intakes are unnecessary for prevention of secondary hyperparathyroidism in subjects with 25(OH)D levels above 75 nmol/liter.

LDL cholesterol has no involvement in the development of cardiovascular disease.

HNF4A mutations can cause diabetes in mutant carriers by the age of 14 years

Angiotensin converting enzyme inhibitors are associated with increased risk for functional renal insufficiency.

mTORC2 regulates intracellular cysteine levels through xCT inhibition.

There is no association between HNF4A mutations and diabetes risks.


A high microerythrocyte count raises vulnerability to severe anemia in homozygous alpha (+)- thalassemia trait subjects.

Upregulation of mosGCTL-1 is induced upon infection with West Nile virus.

Rapamycin decreases the concentration of triacylglycerols in fruit flies.

The US health care system can save up to $750 million if 7% of patients waiting for kidney transplants participate in the optimized national kidney paired donation program.

Articles published in open access format are less likely to be cited than traditional journals.

Silencing of Bcl2 is important for the maintenance and progression of tumors.

N-terminal cleavage increases success identifying transcription start sites.

In domesticated populations of Saccharomyces cerevisiae, whole chromosome aneuploidy is very uncommon.

Tetraspanin-3 is a causative factor in the development of acute myelogenous leukemia

NOX2-independent pathways can generate peroxynitrite by reacting with nitrogen intermediates.

Tumor necrosis factor alpha (TNF-α) and interleukin-1 (IL-1) are pro-inflammatory cytokines that inhibit IL-6 and IL-10.

Mice without IFN-γ or its receptor are resistant to EAM induced with α-MyHC/CFA.

Helminths interfere with immune system control of macrophages activated by IL-4 favor Mycobacterium tuberculosis replication.

Individuals with low serum vitamin D concentrations have increased risk of multiple sclerosis.

Functional consequences of genomic alterations due to Myelodysplastic syndrome (MDS) are poorly understood due to the lack of an animal model.

Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of African origin.

Deamination of cytidine to uridine on the minus strand of viral DNA results in catastrophic G-to-A mutations in the viral genome.


A total of 1,000 people in the UK are asymptomatic carriers of vCJD infection.

High dietary calcium intakes are unnecessary for prevention of secondary hyperparathyroidism in subjects with 25(OH)D levels above 75 nmol/liter.

Downregulation and mislocalization of Scribble prevents cell transformation and mammary tumorigenesis.

0-dimensional biomaterials show inductive properties.

N-terminal cleavage reduces success identifying transcription start sites.

The risk of breast cancer among parous women increases with placental weight of pregnancies, and this association is strongest for premenopausal breast cancer.

New drugs for tuberculosis often do not penetrate the necrotic portion of a tuberculosis lesion in high concentrations.

Autologous transplantation of mesenchymal stem cells has lower rates of rejection than induction therapy with anti-interleukin-2 receptor antibodies.

Birth-weight is positively associated with breast cancer.

The DdrB protein from Deinococcus radiodurans is an alternative SSB.

Ly49Q directs the organization of neutrophil migration to inflammation sites by regulating membrane raft functions.

Hypoglycemia increases the risk of dementia.

Incidence rates of cervical cancer have increased due to nationwide screening programs based primarily on cytology to detect uterine cervical cancer.

Antiretroviral therapy reduces rates of tuberculosis across a broad range of CD4 strata.

Diabetic patients with acute coronary syndrome experience increased short-term and long-term risk for bleeding events.

Incidence rates of cervical cancer have decreased.

Cataract and trachoma are the primary cause of blindness in Southern Sudan.

High levels of CRP reduces the risk of exacerbations in chronic obstructive pulmonary disease (COPD).

Mice that lack Interferon-γ or its receptor exhibit high resistance to experimental autoimmune myocarditis.

CRP is not predictive of postoperative mortality following Coronary Artery Bypass Graft (CABG) surgery.


ADAR1 binds to Dicer to cleave pre-miRNA.

Insulin increases risk of severe kidney failure.

In transgenic mice harboring green florescent protein under the control of the Sox2 promoter, less than ten percent of the cells with green florescent colocalize with cell proliferation markers.

Discrimination between the initiator and elongation tRNAs depends on the translation initiation factor IF3.

1/2000 in UK have abnormal PrP positivity.

Ribosomopathies have a low degree of cell and tissue specific pathology.

Deletion of αvβ8 does not result in a spontaneous inflammatory phenotype.

Active H. pylori urease has a polymeric structure that compromises two subunits, UreA and UreB.

Most termination events in Okazaki fragments are sequence specific.

Low expression of miR7a exerts a biological function in testis.

Low expression of miR7a does represses target genes and exerts a biological function in ovaries.

The PPR MDA5 has two N-terminal CARD domains.

Cells undergoing methionine restriction may activate miRNAs.

TNFAIP3 is a tumor suppressor in glioblastoma.

ITAM phosphorylation prevents the transfer of the T cell receptor (TCR) signal from the echo-domain to the cytoplasmic tail of the T cell receptor (TCR).

Pseudogene PTENP1 regulates the expression of PTEN by functioning as an miRNA decoy.

Alizarin forms hydrogen bonds with residues involved in PGAM1 substrate binding.

The locus rs647161 is associated with colorectal carcinoma.


Autologous transplantation of mesenchymal stem cells causes a higher rate of opportunistic infections than induction therapy with anti-interleukin-2 receptor antibodies.

Tumor necrosis factor alpha (TNF-α) and interleukin-1 (IL-1) are pro-inflammatory cytokines that inhibit IL-6 and IL-10.

High dietary calcium intakes are unnecessary for prevention of secondary hyperparathyroidism in subjects with 25(OH)D levels above 75 nmol/liter.

Breast cancer development is determined exclusively by genetic factors.

CRP is not predictive of postoperative mortality following Coronary Artery Bypass Graft (CABG) surgery.

Cytosolic proteins bind to iron-responsive elements on mRNAs coding for DMT1. Cytosolic proteins bind to iron-responsive elements on mRNAs coding for proteins involved in iron uptake.

In adult tissue, most T cells are memory T cells.

Up-regulation of the p53 pathway and related molecular events casues cancer resistance and results in a significantly shortened lifespan marked by senescent cells and accelerated organismal aging.

Blocking the interaction between TDP-43 and respiratory complex I proteins ND3 and ND6 leads to increased TDP-43-induced neuronal loss.

PGE 2 promotes intestinal tumor growth by altering the expression of tumor suppressing and DNA repair genes.

AMP-activated protein kinase (AMPK) activation increases inflammation-related fibrosis in the lungs.

ALDH1 expression is associated with better breast cancer outcomes.

Epigenetic modulating agents (EMAs) modulate antitumor immune response in a cancer model system.

ALDH1 expression is associated with poorer prognosis in breast cancer.

CX3CR1 on the Th2 cells promotes airway inflammation.

CX3CR1 on the Th2 cells suppresses airway inflammation.

PD-1 triggering on monocytes reduces IL-10 production by monocytes.


ALDH1 expression is associated with better breast cancer outcomes.

1,000 genomes project enables mapping of genetic sequence variation consisting of rare variants with larger penetrance effects than common variants.

Errors in peripheral IV drug administration are most common during bolus administration and multiple-step medicine preparations.

Cell autonomous sex determination in somatic cells occurs in Passeriformes.

Low nucleosome occupancy correlates with low methylation levels across species.

NR5A2 is important in development of endometrial tissues.

Transferred UCB T cells acquire a memory-like phenotype in recipients.

Headaches are not correlated with cognitive impairment.

Leuko-increased blood increases infectious complications in red blood cell transfusion.

Normal expression of RUNX1 has tumor-promoting effects.

CHEK2 is not associated with breast cancer.

Low expression of miR7a exerts a biological function in testis.

Low expression of miR7a does represses target genes and exerts a biological function in ovaries.

TNFAIP3 is a tumor suppressor in glioblastoma.

GATA-3 is important for hematopoietic stem cell (HSC) function.

Breast cancer development is determined exclusively by genetic factors.


ALDH1 expression is associated with poorer prognosis in breast cancer.

Taking 400mg of α-tocopheryl acetate helps to prevent prostate cancer.

PPAR-RXRs are inhibited by PPAR ligands.

Auditory entrainment is strengthened when people see congruent visual and auditory information.

Omnivores produce less trimethylamine N-oxide from dietary I-carnitine than vegetarians.

CX3CR1 on the Th2 cells impairs T cell survival

5% of perinatal mortality is due to low birth weight.

Obesity is determined solely by environmental factors.

Mercaptopurine is anabolized into the inactive methylmercaptopurine by thiopurine methyltrasnferase (TPMT).

The locus rs647161 is associated with colorectal carcinoma.

The relationship between a breast cancer patient's capacity to metabolize tamoxifen and treatment outcome is dependent on the patient's genetic make-up.


AMP-activated protein kinase (AMPK) activation increases inflammation-related fibrosis in the lungs.

0-dimensional biomaterials show inductive properties.

High levels of copeptin decrease risk of diabetes.

Functional consequences of genomic alterations due to Myelodysplastic syndrome (MDS) are poorly understood due to the lack of an animal model.

Histone demethylase recruitment and a transient decrease in histone methylation is necessary for ligand-dependent induction of transcription by nuclear receptors.

Mice without IFN-γ or its receptor are resistant to EAM induced with α-MyHC/CFA.

Autologous transplantation of mesenchymal stem cells has lower rates of rejection than induction therapy with anti-interleukin-2 receptor antibodies.

Flexible molecules experience greater steric hindrance in the tumor microenviroment than rigid molecules.

Podocytes are motile and migrate in the presence of injury.

The one-child policy has been successful in lowering population growth.

The minor G allele of FOXO3 is related to more severe symptoms of Crohn's Disease.

High levels of CRP reduces the risk of exacerbations in chronic obstructive pulmonary disease (COPD).

Enhanced early production of inflammatory chemokines improves viral control in the lung.

Increased vessel density along with a reduction in fibrosis decreases the efficacy of chemotherapy treatments.

Ly49Q directs the organization of neutrophil migration to inflammation sites by regulating membrane raft functions.

Crosstalk between dendritic cells (DCs) and innate lymphoid cells (ILCs) is important in the regulation of intestinal homeostasis.

The deregulated and prolonged activation of monocytes has deleterious effects in inflammatory diseases.


APOE4 expression in iPSC-derived neurons increases AlphaBeta production and tau phosphorylation causing GABA neuron degeneration.

Incidence of heart failure decreased by 10% in women since 1979.

Ivermectin is used to treat onchocerciasis.

Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of African origin.

Auditory entrainment is strengthened when people see congruent visual and auditory information.

ALDH1 expression is associated with poorer prognosis in breast cancer.

Leuko-increased blood increases infectious complications in red blood cell transfusion.

Venules have a thinner or absent smooth layer compared to arterioles.

The ureABIEFGH gene cluster is induced by nickel (II) ion.

Microarray results from culture-amplified mixtures of serotypes correlate poorly with microarray results from uncultured mixtures.

APOE4 expression in iPSC-derived neurons increases AlphaBeta production and tau phosphorylation, delaying GABA neuron degeneration.

FoxO3a activation in neuronal death is mediated by reactive oxygen species (ROS).

NF2 (Merlin) causes phosphorylation and subsequent cytoplasmic sequestration of YAP in Drosophila by activating LATS1/2 kinases.

NF2 (Merlin) prevents phosphorylation and subsequent cytoplasmic sequestration of YAP in Drosophila.

PD-1 triggering on monocytes reduces IL-10 production by monocytes.

IRG1 has antiviral effects against neurotropic viruses.

Reduced responsiveness to interleukin-2 in regulatory T cells is associated with greater resistance to autoimmune diseases such as Type 1 Diabetes.

Arginine 90 in p150n is important for interaction with EB1.

TNFAIP3 is a tumor suppressor in glioblastoma.


APOE4 expression in iPSC-derived neurons increases AlphaBeta production and tau phosphorylation, delaying GABA neuron degeneration.

Varenicline monotherapy is more effective after 12 weeks of treatment compared to combination nicotine replacement therapies with varenicline or bupropion.

IgA plasma cells that are specific for transglutaminase 2 accumulate in the duodenal mucosa on commencement of a gluten-free diet.

Silencing of Bcl2 is important for the maintenance and progression of tumors.

Hypoglycemia increases the risk of dementia.

Discrimination between the initiator and elongation tRNAs depends on the translation initiation factor IF3.

Chronic aerobic exercise alters endothelial function, improving vasodilating mechanisms mediated by NO.

IRG1 has antiviral effects against neurotropic viruses.

Venules have a larger lumen diameter than arterioles.

Rapamycin decreases the concentration of triacylglycerols in fruit flies.

Modifying the epigenome in the brain affects the normal human aging process by affecting certain genes related to neurogenesis.

p16INK4A accumulation is  linked to an abnormal wound response caused by the microinvasive step of advanced Oral Potentially Malignant Lesions (OPMLs).


Activation of PPM1D suppresses p53 function.

Taxation of sugar-sweetened beverages had no effect on the incidence rate of type II diabetes in India.

PD-1 triggering on monocytes reduces IL-10 production by monocytes.

Many proteins in human cells can be post-translationally modified at lysine residues via acetylation.

CRP is not predictive of postoperative mortality following Coronary Artery Bypass Graft (CABG) surgery.

The relationship between a breast cancer patient's capacity to metabolize tamoxifen and treatment outcome is dependent on the patient's genetic make-up.

Insomnia can be effectively treated with cognitive behavioral therapy.

Crossover hot spots are not found within gene promoters in Saccharomyces cerevisiae.

Febrile seizures reduce the threshold for development of epilepsy.

CX3CR1 on the Th2 cells impairs T cell survival

PKG-la plays an essential role in expression of pain hypersensitivity in PGK-la knockout mice.

Up-regulation of the p53 pathway and related molecular events casues cancer resistance and results in a significantly shortened lifespan marked by senescent cells and accelerated organismal aging.

Pseudogene PTENP1 regulates the expression of PTEN by functioning as an miRNA decoy.

Blocking the interaction between TDP-43 and respiratory complex I proteins ND3 and ND6 leads to increased TDP-43-induced neuronal loss.

PGE 2 promotes intestinal tumor growth by altering the expression of tumor suppressing and DNA repair genes.

PPAR-RXRs are inhibited by PPAR ligands.


Activator-inhibitor pairs are provided dorsally by Admpchordin.

Articles published in open access format are less likely to be cited than traditional journals.

Cytochrome c is released from the mitochondrial intermembrane space to cytosol during apoptosis.

Basophils counteract disease development in patients with systemic lupus erythematosus (SLE).

Reduced responsiveness to interleukin-2 in regulatory T cells is associated with greater resistance to autoimmune diseases such as Type 1 Diabetes.

Venules have a thinner or absent smooth layer compared to arterioles.

Mice defective for deoxyribonucleic acid (DNA) polymerase I (polI) reveal increased sensitivity to ionizing radiation (IR).

Chenodeosycholic acid treatment reduces whole-body energy expenditure.

Synaptic activity enhances local release of brain derived neurotrophic factor from postsynaptic dendrites.

Venules have a larger lumen diameter than arterioles.

Primary pro-inflammatory cytokines induce secondary pro- and anti-inflammatory mediators.

Assembly of invadopodia is triggered by focal generation of phosphatidylinositol-3,4-biphosphate and the activation of the nonreceptor tyrosine kinase Src.

PDPN promotes efficient motility along stromal surfaces by activating the C-type lectin receptor to rearrange the actin cytoskeleton in dendritic cells.

During the primary early antibody response activated B cells migrate toward the inner-and outer paracortical areas where oxysterol accumulation is generated by stromal cells.

The sliding activity of kinesin-8 protein Kip3 promotes bipolar spindle assembly.

Auditory entrainment is strengthened when people see congruent visual and auditory information.

ITAM phosphorylation prevents the transfer of the T cell receptor (TCR) signal from the echo-domain to the cytoplasmic tail of the T cell receptor (TCR).

The arm density of TatAd complexes is due to structural rearrangements within Class1 TatAd complexes such as the 'charge zipper mechanism'.


Active H. pylori urease has a polymeric structure that compromises two subunits, UreA and UreB.

The benefits of colchicine were achieved with effective widespread use of secondary prevention strategies such as high-dose statins.

Homozygous deletion of murine Sbds gene from osterix-expressing mesenchymal stem and progenitor cells (MPCs) prevents oxidative stress.

Fz/PCP-dependent Pk localizes to the anterior membrane of neuroectoderm cells during zebrafish neuralation

Errors in peripheral IV drug administration are most common during bolus administration and multiple-step medicine preparations.

Low nucleosome occupancy correlates with low methylation levels across species.

Pyridostatin destabilizes the G - quadruplex in the telomeric region.

In young and middle-aged adults, current or remote uses of ADHD medications do not increase the risk of serious cardiovascular events.

Macropinocytosis contributes to a cell's supply of amino acids via the intracellular uptake of protein.

Lymphadenopathy is observed in knockin mouse lacking the SHP-2 MAPK pathway.

The ureABIEFGH gene cluster encodes urease maturation proteins : UreD/UreH, UreE, UreF, and UreG.

The ureABIEFGH gene cluster is induced by nickel (II) ion.

Mercaptopurine is anabolized into the inactive methylmercaptopurine by thiopurine methyltrasnferase (TPMT).

NOX2-independent pathways can generate peroxynitrite by reacting with nitrogen intermediates.

Ethanol stress decreases the expression of IBP in bacteria.

Peroxynitrite is required for nitration of TCR/CD8.

Deamination of cytidine to uridine on the minus strand of viral DNA results in catastrophic G-to-A mutations in the viral genome.

The composition of myosin-II isoform switches from the polarizable B isoform to the more homogenous A isoform during hematopoietic differentiation.

Helminths interfere with immune system control of macrophages activated by IL-4 favor Mycobacterium tuberculosis replication.


Albendazole is used to treat lymphatic filariasis.

Pyridostatin destabilizes the G - quadruplex in the telomeric region.

Antibiotic induced alterations in the gut microbiome reduce resistance against Clostridium difficile

Female carriers of the Apolipoprotein E4 (APOE4) allele have increased risk for dementia.

The one-child policy has been successful in lowering population growth.

Macrolides protect against myocardial infarction.

HNF4A mutations can cause diabetes in mutant carriers by the age of 14 years

Leuko-reduced blood reduces infectious complications in red blood cell transfusion.

The treatment of cancer patients with co-IR blockade does not cause any adverse autoimmune events.

Only a minority of cells survive development after differentiation into stress-resistant spores.

Angiotensin converting enzyme inhibitors are associated with increased risk for functional renal insufficiency.

Ivermectin is used to treat lymphatic filariasis.

Increased vessel density along with a reduction in fibrosis decreases the efficacy of chemotherapy treatments.

Ivermectin is used to treat onchocerciasis.

Metastatic colorectal cancer treated with a single agent fluoropyrimidines resulted in reduced efficacy and lower quality of life when compared with oxaliplatin-based chemotherapy in elderly patients.

Tetraspanin-3 is a causative factor in the development of acute myelogenous leukemia

Therapeutic use of the drug Dapsone to treat pyoderma gangrenous is based on anecdotal evidence.

Varenicline monotherapy is more effective after 12 weeks of treatment compared to combination nicotine replacement therapies with varenicline or bupropion.

AMP-activated protein kinase (AMPK) activation increases inflammation-related fibrosis in the lungs.


Alizarin forms hydrogen bonds with residues involved in PGAM1 substrate binding.

The center of the granuloma in an immune cell induces a pro-inflammatory immune response.

The risk of breast cancer among parous women increases with placental weight of pregnancies, and this association is strongest for premenopausal breast cancer.

The ureABIEFGH gene cluster encodes urease maturation proteins : UreD/UreH, UreE, UreF, and UreG.

Mice defective for deoxyribonucleic acid (DNA) polymerase I (polI) reveal increased sensitivity to ionizing radiation (IR).

Occupancy of ribosomes by IncRNAs do not make functional peptides.

ALDH1 expression is associated with poorer prognosis in breast cancer.

FoxO3a activation in neuronal death is mediated by reactive oxygen species (ROS).

NFAT4 activation requires IP3R-mediated Ca2+ mobilization.

Pleiotropic coupling of GLP-1R to intracellular effectors promotes distinct profiles of cellular signaling.

Downregulation and mislocalization of Scribble prevents cell transformation and mammary tumorigenesis.

Many proteins in human cells can be post-translationally modified at lysine residues via acetylation.

The PPR MDA5 has two N-terminal CARD domains.

Mercaptopurine is anabolized into the inactive methylmercaptopurine by thiopurine methyltrasnferase (TPMT).

ADAR1 binds to Dicer to cleave pre-miRNA.

Active H. pylori urease has a polymeric structure that compromises two subunits, UreA and UreB.

Aspirin inhibits the production of PGE2.

Localization of PIN1 in the Arabidopsis embryo does not require VPS9a

Localization of PIN1 in the roots of Arabidopsis does not require VPS9a


All hematopoietic stem cells segregate their chromosomes randomly.

Macrolides have no protective effect against myocardial infarction.

Integrating classroom-based collaborative learning with Web-based collaborative learning leads to subpar class performance

PDPN promotes efficient motility along stromal surfaces by activating the C-type lectin receptor to rearrange the actin cytoskeleton in dendritic cells.

Glycolysis is one of the primary glycometabolic pathways in cells.

Enhanced early production of inflammatory chemokines improves viral control in the lung.

Transplanted human glial cells can differentiate within the host animal.

Rapid phosphotransfer rates govern fidelity in two component systems

Free histones are degraded by a Rad53-dependent mechanism once DNA has been replicated.

There is no association between HNF4A mutations and diabetes risks.

Arginine 90 in p150n is important for interaction with EB1.

Hematopoietic Stem Cell purification reaches purity rate of up to 50%.

GATA-3 is important for hematopoietic stem cell (HSC) function.

Gene expression does not vary appreciably across genetically identical cells.

In domesticated populations of Saccharomyces cerevisiae, whole chromosome aneuploidy is very uncommon.

The myocardial lineage develops from cardiac progenitors of mesodermal origin.

Bone marrow cells contribute to adult macrophage compartments.

0-dimensional biomaterials show inductive properties.

Breast cancer development is determined exclusively by genetic factors.


Angiotensin converting enzyme inhibitors are associated with increased risk for functional renal insufficiency.

CX3CR1 on the Th2 cells impairs T cell survival

CX3CR1 on the Th2 cells promotes T cell survival

Venules have a thinner or absent smooth layer compared to arterioles.

p16INK4A accumulation is  linked to an abnormal wound response caused by the microinvasive step of advanced Oral Potentially Malignant Lesions (OPMLs).

Bariatric surgery has a positive impact on mental health.

In adult tissue, most T cells are memory T cells.

The repair of Cas9-induced double strand breaks in human DNA is error-prone.

Localization of PIN1 in the roots of Arabidopsis does not require VPS9a

Insulin increases risk of severe kidney failure.

The US health care system can save up to $750 million if 7% of patients waiting for kidney transplants participate in the optimized national kidney paired donation program.

A deficiency of vitamin B12 increases blood levels of homocysteine.

High dietary calcium intakes are unnecessary for prevention of secondary hyperparathyroidism in subjects with 25(OH)D levels above 75 nmol/liter.

Chenodeosycholic acid treatment reduces whole-body energy expenditure.

Chenodeosycholic acid treatment increases whole-body energy expenditure.

LDL cholesterol has no involvement in the development of cardiovascular disease.


Anthrax spores can be disposed of easily after they are dispersed.

Taxation of sugar-sweetened beverages had no effect on the incidence rate of type II diabetes in India.

Insulin increases risk of severe kidney failure.

HNF4A mutations can cause diabetes in mutant carriers by the age of 14 years

The PRR MDA5 has a central DExD/H RNA helices domain.

The tip of the inner tube of the toxic type VI secretion system (T6SS) antibacterial effector in Escherichia coli (E. coli) carries toxic effector proteins.

Synaptic activity enhances local release of brain derived neurotrophic factor from postsynaptic dendrites.

PPAR-RXRs are inhibited by PPAR ligands.

Functional consequences of genomic alterations due to Myelodysplastic syndrome (MDS) are poorly understood due to the lack of an animal model.

Proteins synthesized at the growth cone are ubiquitinated at a higher rate than proteins from the cell body.

Only a minority of cells survive development after differentiation into stress-resistant spores.

New drugs for tuberculosis often do not penetrate the necrotic portion of a tuberculosis lesion in high concentrations.

In mice, P. chabaudi parasites are able to proliferate faster early in infection when inoculated at lower numbers than when inoculated at high numbers.

In domesticated populations of Saccharomyces cerevisiae, whole chromosome aneuploidy is very uncommon.

The center of the granuloma in an immune cell induces a pro-inflammatory immune response.

High levels of CRP reduces the risk of exacerbations in chronic obstructive pulmonary disease (COPD).

Helminths interfere with immune system control of macrophages activated by IL-4 favor Mycobacterium tuberculosis replication.

All hematopoietic stem cells segregate their chromosomes randomly.

Enhanced early production of inflammatory chemokines improves viral control in the lung.


Antibiotic induced alterations in the gut microbiome reduce resistance against Clostridium difficile

Immune complex triggered cell death leads to extracellular release of neutrophil protein HMGB1.

Discrimination between the initiator and elongation tRNAs depends on the translation initiation factor IF3.

Cellular aging closely links to an older appearance.

Smc5/6 engagment drives the activation of SUMO E3 ligase Mms21 by ATP-dependent remolding.

Diabetic patients with acute coronary syndrome experience increased short-term and long-term risk for bleeding events.

Deletion of αvβ8 does not result in a spontaneous inflammatory phenotype.

Commelina yellow mottle virus' (ComYMV) genome consists of 7489 baise pairs.

Thigh-length graduated compression stockings (GCS) did not reduce deep vein thrombosis in patients admitted to hospital who are immobile because of acute stroke.

Ethanol stress decreases the expression of IBP in bacteria.

Deamination of cytidine to uridine on the minus strand of viral DNA results in catastrophic G-to-A mutations in the viral genome.

Mathematical models predict that using Artemisinin-based combination therapy over nongametocytocidal drugs have a dramatic impact in reducing malaria transmission.

Active H. pylori urease has a polymeric structure that compromises two subunits, UreA and UreB.

Mercaptopurine is anabolized into the inactive methylmercaptopurine by thiopurine methyltrasnferase (TPMT).

Arginine 90 in p150n is important for interaction with EB1.


Antiretroviral therapy reduces rates of tuberculosis across a broad range of CD4 strata.

Hypothalamic glutamate neurotransmission is crucial to energy balance.

Crosstalk between dendritic cells (DCs) and innate lymphoid cells (ILCs) is important in the regulation of intestinal homeostasis.

The risk of male prisoners harming themselves is ten times that of female prisoners.

Combination nicotine replacement therapies with varenicline or bupropion lead to significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

Arginine 90 in p150n is important for interaction with EB1.

All hematopoietic stem cells segregate their chromosomes randomly.

Varenicline monotherapy is more effective after 12 weeks of treatment compared to combination nicotine replacement therapies with varenicline or bupropion.

Aspirin inhibits the production of PGE2.

Polymeal nutrition reduces cardiovascular mortality.

Taxation of sugar-sweetened beverages had no effect on the incidence rate of type II diabetes in India.

Hypoglycemia increases the risk of dementia.

Deletion of αvβ8 does not result in a spontaneous inflammatory phenotype.

Mice that lack Interferon-γ or its receptor exhibit high resistance to experimental autoimmune myocarditis.

The benefits of colchicine were achieved with effective widespread use of secondary prevention strategies such as high-dose statins.


Arginine 90 in p150n is important for interaction with EB1.

Incidence of heart failure decreased by 10% in women since 1979.

UCB T cells reduce TCR diversity after transplantation.

In young and middle-aged adults, current or remote uses of ADHD medications do not increase the risk of serious cardiovascular events.

Anthrax spores can be disposed of easily after they are dispersed.

Active H. pylori urease has a polymeric structure that compromises two subunits, UreA and UreB.

Ethanol stress decreases the expression of IBP in bacteria.

Deletion of αvβ8 does not result in a spontaneous inflammatory phenotype.

Most termination events in Okazaki fragments are sequence specific.

Auditory entrainment is strengthened when people see congruent visual and auditory information.

Rapid up-regulation and higher basal expression of interferon-induced genes reduce survival of granule cell neurons that are infected by West Nile virus.

The ureABIEFGH gene cluster is induced by nickel (II) ion.

N348I mutations cause resistance to zidovudine (AZT).

Mutations in G-Beta protein GNB2 are present in many cancers, resulting in loss of interaction with G-alpha subunits and concomitant activation of AKT pathway.

Ubiquitin ligase UBC13 generates a K63-linked polyubiquitin moiety at PCNA K164.

NR5A2 is important in development of endometrial tissues.

p16INK4A accumulation is  linked to an abnormal wound response caused by the microinvasive step of advanced Oral Potentially Malignant Lesions (OPMLs).

IRG1 has antiviral effects against neurotropic viruses.

APOE4 expression in iPSC-derived neurons increases AlphaBeta production and tau phosphorylation, delaying GABA neuron degeneration.

The extracellular domain of TMEM27 is cleaved in human beta cells.


Arterioles have a larger lumen diameter than venules.

Functional consequences of genomic alterations due to Myelodysplastic syndrome (MDS) are poorly understood due to the lack of an animal model.

MicroRNA is involved in the regulation of Neural Stem Cell (NSC) differentiation and proliferation dynamic homeostasis

In mice, P. chabaudi parasites are able to proliferate faster early in infection when inoculated at lower numbers than when inoculated at high numbers.

Primary pro-inflammatory cytokines induce secondary pro- and anti-inflammatory mediators.

The treatment of cancer patients with co-IR blockade does not cause any adverse autoimmune events.

Ly49Q directs the organization of neutrophil migration to inflammation sites by regulating membrane raft functions.

Non-invasive ventilation use should be decreased if there is inadequate response to conventional treatment.

mTORC2 regulates intracellular cysteine levels through xCT inhibition.

Pyridostatin destabilizes the G - quadruplex in the telomeric region.

Lymphadenopathy is observed in knockin mouse lacking the SHP-2 MAPK pathway.

Venules have a larger lumen diameter than arterioles.

Venules have a thinner or absent smooth layer compared to arterioles.

Flexible molecules experience greater steric hindrance in the tumor microenviroment than rigid molecules.

Podocytes are motile and migrate in the presence of injury.

PDPN promotes efficient motility along stromal surfaces by activating the C-type lectin receptor to rearrange the actin cytoskeleton in dendritic cells.

Nanoparticles can be targeted against specific cell types by incorporating aptamers into lipid nanoparticles.

The arm density of TatAd complexes is due to structural rearrangements within Class1 TatAd complexes such as the 'charge zipper mechanism'.

0-dimensional biomaterials show inductive properties.


Articles published in open access format are less likely to be cited than traditional journals.

Cell autonomous sex determination in somatic cells occurs in Passeriformes.

Chenodeosycholic acid treatment reduces whole-body energy expenditure.

TNFAIP3 is a tumor suppressor in glioblastoma.

Upregulation of mosGCTL-1 is induced upon infection with West Nile virus.

Immune complex triggered cell death leads to extracellular release of neutrophil protein HMGB1.

The extracellular domain of TMEM27 is cleaved in human beta cells.

Less than 10% of the gabonese children with Schimmelpenning-Feuerstein-Mims syndrome (SFM) had a plasma lactate of more than 5mmol/L.

Chenodeosycholic acid treatment increases whole-body energy expenditure.

The arm density of TatAd complexes is due to structural rearrangements within Class1 TatAd complexes such as the 'charge zipper mechanism'.

Articles published in open access format are more likely to be cited than traditional journals.

The amount of publicly available DNA data doubles every 10 years.

Teaching hospitals do not provide better care than non-teaching hospitals.

De novo assembly of sequence data has more specific contigs than unassembled sequence data.

Integrating classroom-based collaborative learning with Web-based collaborative learning leads to subpar class performance

Epidemiological disease burden from noncommunicable diseases is more prevalent in low economic settings.

Patients in stable partnerships have a faster progression from HIV to AIDS.

The availability of safe places to study is effective at decreasing homelessness.

The availability of safe places to study is not effective at decreasing homelessness.


Articles published in open access format are more likely to be cited than traditional journals.

The ureABIEFGH gene cluster encodes urease maturation proteins : UreD/UreH, UreE, UreF, and UreG.

Mercaptopurine is anabolized into the inactive methylmercaptopurine by thiopurine methyltrasnferase (TPMT).

The composition of myosin-II isoform switches from the polarizable B isoform to the more homogenous A isoform during hematopoietic differentiation.

Hypothalamic glutamate neurotransmission is crucial to energy balance.

Activator-inhibitor pairs are provided dorsally by Admpchordin.

Commelina yellow mottle virus' (ComYMV) genome consists of 7489 baise pairs.

Macropinocytosis contributes to a cell's supply of amino acids via the intracellular uptake of protein.


Aspirin inhibits the production of PGE2.

NFAT4 activation requires IP3R-mediated Ca2+ mobilization.

Bone marrow cells contribute to adult macrophage compartments.

The loss of the TET protein functions may have dire biological consequences, such as myeloid cancers.

Synaptic activity enhances local release of brain derived neurotrophic factor from postsynaptic dendrites.

MicroRNA is involved in the regulation of Neural Stem Cell (NSC) differentiation and proliferation dynamic homeostasis

The combination of H3K4me3 and H3K79me2 is found in quiescent hair follicle stem cells.

Ultrasound guidance significantly raises the number of traumatic procedures when attempting needle insertion.

Pyridostatin destabilizes the G - quadruplex in the telomeric region.

Golli-deficient T-cells prefer to differentiate into an anergic phenotype in the adaptive immune response when there are increased levels of Ca2+ in the cytosol.

PGE 2 promotes intestinal tumor growth by altering the expression of tumor suppressing and DNA repair genes.

PKG-la plays an essential role in expression of pain hypersensitivity in PGK-la knockout mice.

Sildenafil improves erectile function in men who experience sexual dysfunction as a result of the use of SSRI antidepressants.

Alizarin forms hydrogen bonds with residues involved in PGAM1 substrate binding.

Activation of PPM1D suppresses p53 function.

PD-1 triggering on monocytes reduces IL-10 production by monocytes.

Arginine 90 in p150n is important for interaction with EB1.

Ethanol stress decreases the expression of IBP in bacteria.

Mutant mice lacking SVCT2 have greatly increased ascorbic acid levels in both brain and adrenals.


Assembly of invadopodia is triggered by focal generation of phosphatidylinositol-3,4-biphosphate and the activation of the nonreceptor tyrosine kinase Src.

Low expression of miR7a exerts a biological function in testis.

There is an inverse relationship between hip fractures and statin use.

Input from  mental and physical health care professionals is effective at decreasing homelessness.

Venules have a thinner or absent smooth layer compared to arterioles.

Integrating classroom-based collaborative learning with Web-based collaborative learning leads to subpar class performance

Reduced responsiveness to interleukin-2 in regulatory T cells is associated with greater resistance to autoimmune diseases such as Type 1 Diabetes.

Low nucleosome occupancy correlates with low methylation levels across species.

Pseudogene PTENP1 regulates the expression of PTEN by functioning as an miRNA decoy.

A deficiency of vitamin B12 increases blood levels of homocysteine.

Cells undergoing methionine restriction may activate miRNAs.

Activator-inhibitor pairs are provided dorsally by Admpchordin.

The single flash-evoked ERG b-wave is generated by activity of ON-bipolar cells.

PDPN promotes efficient motility along stromal surfaces by activating the C-type lectin receptor to rearrange the actin cytoskeleton in dendritic cells.

The sliding activity of kinesin-8 protein Kip3 promotes bipolar spindle assembly.

Podocytes are motile and migrate in the presence of injury.

Mitochondria are uninvolved in apoptosis.

During the primary early antibody response activated B cells migrate toward the inner-and outer paracortical areas where oxysterol accumulation is generated by stromal cells.

Synaptic activity enhances local release of brain derived neurotrophic factor from postsynaptic dendrites.

ITAM phosphorylation prevents the transfer of the T cell receptor (TCR) signal from the echo-domain to the cytoplasmic tail of the T cell receptor (TCR).


Asymptomatic visual impairment screening in elderly populations does not lead to improved vision.

Headaches are not correlated with cognitive impairment.

Cytosolic proteins bind to iron-responsive elements on mRNAs coding for DMT1. Cytosolic proteins bind to iron-responsive elements on mRNAs coding for proteins involved in iron uptake.

Hyperfibrinogenemia decreases rates of femoropopliteal bypass thrombosis.

Microarray results from culture-amplified mixtures of serotypes correlate poorly with microarray results from uncultured mixtures.

PPAR-RXRs can be activated by PPAR ligands.

ITAM phosphorylation prevents the transfer of the T cell receptor (TCR) signal from the echo-domain to the cytoplasmic tail of the T cell receptor (TCR).

High-sensitivity cardiac troponin T (HSCT-T) dosage may not be diagnostic if the onset of symptoms occurs less than 3 hours before acute myocardial injury (AMI).

Silencing of Bcl2 is important for the maintenance and progression of tumors.

Pyridostatin destabilizes the G - quadruplex in the telomeric region.

In young and middle-aged adults, current or remote uses of ADHD medications do not increase the risk of serious cardiovascular events.

Hypoglycemia increases the risk of dementia.

Auditory entrainment is strengthened when people see congruent visual and auditory information.

Female carriers of the Apolipoprotein E4 (APOE4) allele have increased risk for dementia.

Cataract and trachoma are the primary cause of blindness in Southern Sudan.

Hypertension is frequently observed in type 1 diabetes patients.

Insomnia can be effectively treated with cognitive behavioral therapy.

CRP is not predictive of postoperative mortality following Coronary Artery Bypass Graft (CABG) surgery.


Auditory entrainment is strengthened when people see congruent visual and auditory information.

The single flash-evoked ERG b-wave is generated by activity of ON-bipolar cells.

Flexible molecules experience greater steric hindrance in the tumor microenviroment than rigid molecules.

Rapid up-regulation and higher basal expression of interferon-induced genes reduce survival of granule cell neurons that are infected by West Nile virus.

T regulatory cells (tTregs) lacking αvβ8 are more adept at suppressing pathogenic T-cell responses during active inflammation.

All hematopoietic stem cells segregate their chromosomes randomly.

Ivermectin is used to treat onchocerciasis.

Epidemiological disease burden from noncommunicable diseases is more prevalent in low economic settings.

New drugs for tuberculosis often do not penetrate the necrotic portion of a tuberculosis lesion in high concentrations.

Female carriers of the Apolipoprotein E4 (APOE4) allele have increased risk for dementia.

Hypothalamic glutamate neurotransmission is crucial to energy balance.

Ultrasound guidance significantly raises the number of traumatic procedures when attempting needle insertion.

Activator-inhibitor pairs are provided dorsally by Admpchordin.

Exposure to fine particulate air pollution is relate to anxiety prevalence.

Crosstalk between dendritic cells (DCs) and innate lymphoid cells (ILCs) is important in the regulation of intestinal homeostasis.

Synaptic activity enhances local release of brain derived neurotrophic factor from postsynaptic dendrites.


Autologous transplantation of mesenchymal stem cells causes a higher rate of opportunistic infections than induction therapy with anti-interleukin-2 receptor antibodies.

Bone marrow cells contribute to adult macrophage compartments.

Ubiquitin ligase UBC13 generates a K63-linked polyubiquitin moiety at PCNA K164.

Only a minority of cells survive development after differentiation into stress-resistant spores.

Cellular aging closely links to an older appearance.

PD-1 triggering on monocytes reduces IL-10 production by monocytes.

Combination nicotine replacement therapies with varenicline or bupropion lead to significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

Ribosomopathies have a low degree of cell and tissue specific pathology.

Lupus-prone mice infected with curliproducing bacteria have higher autoantibody titers compared to controls.

mTORC2 regulates intracellular cysteine levels through xCT inhibition.

Autologous transplantation of mesenchymal stem cells causes fewer opportunistic infections than induction therapy with anti-interleukin-2 receptor antibodies.

Autologous transplantation of mesenchymal stem cells has lower rates of rejection than induction therapy with anti-interleukin-2 receptor antibodies.

Increased vessel density along with a reduction in fibrosis decreases the efficacy of chemotherapy treatments.

Immune responses result in the development of inflammatory Th17 cells and anti-inflammatory iTregs.

Epigenetic modulating agents (EMAs) modulate antitumor immune response in a cancer model system.

Golli-deficient T-cells prefer to differentiate into an anergic phenotype in the adaptive immune response when there are increased levels of Ca2+ in the cytosol.

Homozygous deletion of murine Sbds gene from osterix-expressing mesenchymal stem and progenitor cells (MPCs) prevents oxidative stress.

Reduced responsiveness to interleukin-2 in regulatory T cells is associated with greater resistance to autoimmune diseases such as Type 1 Diabetes.

The treatment of cancer patients with co-IR blockade precipitates adverse autoimmune events.


Autologous transplantation of mesenchymal stem cells causes fewer opportunistic infections than induction therapy with anti-interleukin-2 receptor antibodies.

Proteins synthesized at the growth cone are ubiquitinated at a higher rate than proteins from the cell body.

Golli-deficient T-cells prefer to differentiate into an anergic phenotype in the adaptive immune response when there are increased levels of Ca2+ in the cytosol.

In young and middle-aged adults, current or remote uses of ADHD medications do not increase the risk of serious cardiovascular events.

Basophils counteract disease development in patients with systemic lupus erythematosus (SLE).

Activator-inhibitor pairs are provided dorsally by Admpchordin.

Rapid phosphotransfer rates govern fidelity in two component systems

A high microerythrocyte count raises vulnerability to severe anemia in homozygous alpha (+)- thalassemia trait subjects.

Primary pro-inflammatory cytokines induce secondary pro- and anti-inflammatory mediators.

Macrolides have no protective effect against myocardial infarction.

PGE 2 promotes intestinal tumor growth by altering the expression of tumor suppressing and DNA repair genes.

Mice that lack Interferon-γ or its receptor exhibit high resistance to experimental autoimmune myocarditis.

Stroke patients with prior use of direct oral anticoagulants have a lower risk of in-hospital mortality than stroke patients with prior use of warfarin.


Autologous transplantation of mesenchymal stem cells has lower rates of rejection than induction therapy with anti-interleukin-2 receptor antibodies.

The risk of male prisoners harming themselves is ten times that of female prisoners.

A total of 1,000 people in the UK are asymptomatic carriers of vCJD infection.

cSMAC formation enhances weak ligand signalling.

T regulatory cells (tTregs) lacking αvβ8 are more adept at suppressing pathogenic T-cell responses during active inflammation.

Most termination events in Okazaki fragments are sequence specific.

Low expression of miR7a does represses target genes and exerts a biological function in ovaries.

Up-regulation of the p53 pathway and related molecular events casues cancer resistance and results in a significantly shortened lifespan marked by senescent cells and accelerated organismal aging.

The US health care system can save up to $750 million if 7% of patients waiting for kidney transplants participate in the optimized national kidney paired donation program.

Chronic aerobic exercise alters endothelial function, improving vasodilating mechanisms mediated by NO.

UCB T cells reduce TCR diversity after transplantation.

UCB T cells maintain high TCR diversity after transplantation.


Glycolysis is one of the primary glycometabolic pathways in cells.

The sliding activity of kinesin-8 protein Kip3 promotes bipolar spindle assembly.

Radioiodine treatment of non-toxic multinodular goitre reduces thyroid volume.

ALDH1 expression is associated with better breast cancer outcomes.

Errors in peripheral IV drug administration are most common during bolus administration and multiple-step medicine preparations.

Antibiotic induced alterations in the gut microbiome reduce resistance against Clostridium difficile

Cell autonomous sex determination in somatic cells does not occur in Galliformes.

Cell autonomous sex determination in somatic cells occurs in Passeriformes.

The DdrB protein from Deinococcus radiodurans is an alternative SSB.

Cellular aging closely links to an older appearance.

Hypoglycemia increases the risk of dementia.

Ethanol stress decreases the expression of IBP in bacteria.

Low nucleosome occupancy correlates with low methylation levels across species.

Epidemiological disease burden from noncommunicable diseases is more prevalent in low economic settings.

Modifying the epigenome in the brain affects the normal human aging process by affecting certain genes related to neurogenesis.

Obesity is determined solely by environmental factors.

Female carriers of the Apolipoprotein E4 (APOE4) allele have increased risk for dementia.


Bariatric surgery has a positive impact on mental health.

Epigenetic modulating agents (EMAs) modulate antitumor immune response in a cancer model system.

The myocardial lineage develops from cardiac progenitors of mesodermal origin.

NR5A2 is important in development of endometrial tissues.

The center of the granuloma in an immune cell induces a pro-inflammatory immune response.

Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink less that non-carries.

Arginine 90 in p150n is important for interaction with EB1.

Therapeutic use of the drug Dapsone to treat pyoderma gangrenous is based on anecdotal evidence.

Bone marrow cells contribute to adult macrophage compartments.

The treatment of cancer patients with co-IR blockade precipitates adverse autoimmune events.

Glycolysis is one of the primary glycometabolic pathways in cells.

Teaching hospitals do not provide better care than non-teaching hospitals.

Functional consequences of genomic alterations due to Myelodysplastic syndrome (MDS) are poorly understood due to the lack of an animal model.

There is an inverse relationship between hip fractures and statin use.

Input from  mental and physical health care professionals is effective at decreasing homelessness.

Thigh-length graduated compression stockings (GCS) did not reduce deep vein thrombosis in patients admitted to hospital who are immobile because of acute stroke.

Vitamin D deficiency effects the term of delivery.

Ultrasound guidance significantly raises the number of traumatic procedures when attempting needle insertion.

CRP is not predictive of postoperative mortality following Coronary Artery Bypass Graft (CABG) surgery.

Healthcare delivery efficiency in crowded delivery centers is impaired by improving structural, logistical, and interpersonal elements.


Basophils counteract disease development in patients with systemic lupus erythematosus (SLE).

AMP-activated protein kinase (AMPK) activation increases inflammation-related fibrosis in the lungs.

Deletion of αvβ8 does not result in a spontaneous inflammatory phenotype.

CRP is not predictive of postoperative mortality following Coronary Artery Bypass Graft (CABG) surgery.

Localization of PIN1 in the Arabidopsis embryo does not require VPS9a

Hyperfibrinogenemia decreases rates of femoropopliteal bypass thrombosis.

Macropinocytosis contributes to a cell's supply of amino acids via the intracellular uptake of protein.

Venules have a larger lumen diameter than arterioles.

PD-1 triggering on monocytes reduces IL-10 production by monocytes.

Leuko-reduced blood reduces infectious complications in red blood cell transfusion.

Helminths interfere with immune system control of macrophages activated by IL-4 favor Mycobacterium tuberculosis replication.

Neutrophil extracellular traps (NETs) are released by ANCA-stimulated neutrophils.

Mice that lack Interferon-γ or its receptor exhibit high resistance to experimental autoimmune myocarditis.

Lupus-prone mice infected with curliproducing bacteria have higher autoantibody titers compared to controls.

Increased vessel density along with a reduction in fibrosis decreases the efficacy of chemotherapy treatments.

Macrolides protect against myocardial infarction.

LDL cholesterol has no involvement in the development of cardiovascular disease.

Macrolides have no protective effect against myocardial infarction.


Birth-weight is positively associated with breast cancer.

Combining phosphatidylinositide 3-kinase and MEK 1/2 inhibitors is effective at treating KRAS mutant tumors.

Activator-inhibitor pairs are provided dorsally by Admpchordin.

Errors in peripheral IV drug administration are most common during bolus administration and multiple-step medicine preparations.

Breast cancer development is determined exclusively by genetic factors.

UCB T cells maintain high TCR diversity after transplantation.

The YAP1 and TEAD complex tanslocates into the nucleus where it interacts with transcription factors and DNA-binding proteins that modulate target gene transcription.

During the primary early antibody response activated B cells migrate toward the inner-and outer paracortical areas where oxysterol accumulation is generated by stromal cells.

Neutrophil extracellular traps (NETs) are released by ANCA-stimulated neutrophils.

Glycolysis is one of the primary glycometabolic pathways in cells.

Women with a higher birth weight are more likely to develop breast cancer later in life.

5% of perinatal mortality is due to low birth weight.

The risk of breast cancer among parous women increases with placental weight of pregnancies, and this association is strongest for premenopausal breast cancer.

Vitamin D deficiency is unrelated to birth weight.

Incidence rates of cervical cancer have increased due to nationwide screening programs based primarily on cytology to detect uterine cervical cancer.

Incidence rates of cervical cancer have decreased.

Female carriers of the Apolipoprotein E4 (APOE4) allele have increased risk for dementia.

CHEK2 is not associated with breast cancer.


Blocking the interaction between TDP-43 and respiratory complex I proteins ND3 and ND6 leads to increased TDP-43-induced neuronal loss.

Localization of PIN1 in the roots of Arabidopsis does not require VPS9a

Mutations in G-Beta protein GNB2 are present in many cancers, resulting in loss of interaction with G-alpha subunits and concomitant activation of AKT pathway.

Flexible molecules experience greater steric hindrance in the tumor microenviroment than rigid molecules.

Sildenafil improves erectile function in men who experience sexual dysfunction as a result of the use of SSRI antidepressants.

Histone demethylase recruitment and a transient decrease in histone methylation is necessary for ligand-dependent induction of transcription by nuclear receptors.

A high microerythrocyte count raises vulnerability to severe anemia in homozygous alpha (+)- thalassemia trait subjects.

PPAR-RXRs are inhibited by PPAR ligands.

Anthrax spores can be disposed of easily after they are dispersed.

PDPN promotes efficient motility along stromal surfaces by activating the C-type lectin receptor to rearrange the actin cytoskeleton in dendritic cells.

NFAT4 activation requires IP3R-mediated Ca2+ mobilization.

ITAM phosphorylation prevents the transfer of the T cell receptor (TCR) signal from the echo-domain to the cytoplasmic tail of the T cell receptor (TCR).

Reduced responsiveness to interleukin-2 in regulatory T cells is associated with greater resistance to autoimmune diseases such as Type 1 Diabetes.

Ly49Q directs the organization of neutrophil migration to inflammation sites by regulating membrane raft functions.

CX3CR1 on the Th2 cells suppresses airway inflammation.

PD-1 triggering on monocytes reduces IL-10 production by monocytes.

CX3CR1 on the Th2 cells promotes airway inflammation.

NF2 (Merlin) causes phosphorylation and subsequent cytoplasmic sequestration of YAP in Drosophila by activating LATS1/2 kinases.

Activation of PPM1D suppresses p53 function.

S-nitrosylated GAPDH physiologically transnitrosylates histone deacetylases.


Bone marrow cells contribute to adult macrophage compartments.

ITAM phosphorylation prevents the transfer of the T cell receptor (TCR) signal from the echo-domain to the cytoplasmic tail of the T cell receptor (TCR).

The risk of male prisoners harming themselves is ten times that of female prisoners.

The sliding activity of kinesin-8 protein Kip3 promotes bipolar spindle assembly.

Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink less that non-carries.

Ly6C hi monocytes have a lower inflammatory capacity compared to their Ly6C lo counterparts.

CR is associated with higher methylation age.

Epigenetic modulating agents (EMAs) modulate antitumor immune response in a cancer model system.

Mitochondria are uninvolved in apoptosis.

CRP is not predictive of postoperative mortality following Coronary Artery Bypass Graft (CABG) surgery.

The extracellular domain of TMEM27 is cleaved in human beta cells.

Transplanted human glial cells can differentiate within the host animal.

Macropinocytosis contributes to a cell's supply of amino acids via the intracellular uptake of protein.

The myocardial lineage develops from cardiac progenitors of mesodermal origin.

Transplanted human glial progenitor cells are incapable of forming a neural network with host animals' neurons.

Glycolysis is one of the primary glycometabolic pathways in cells.

The deregulated and prolonged activation of monocytes has deleterious effects in inflammatory diseases.

In adult tissue, most T cells are memory T cells.

Ly6C hi monocytes have a lower inflammatory capacity than Ly6C lo monocytes.


Breast cancer development is determined exclusively by genetic factors.

Alizarin forms hydrogen bonds with residues involved in PGAM1 substrate binding.

Stroke patients with prior use of direct oral anticoagulants have a lower risk of in-hospital mortality than stroke patients with prior use of warfarin.

UCB T cells reduce TCR diversity after transplantation.

Patients in stable partnerships have a faster progression from HIV to AIDS.

Chronic aerobic exercise alters endothelial function, improving vasodilating mechanisms mediated by NO.

Bone marrow cells contribute to adult macrophage compartments.

T regulatory cells (tTregs) lacking αvβ8 are more adept at suppressing pathogenic T-cell responses during active inflammation.

High levels of copeptin decrease risk of diabetes.

Podocytes are motile and migrate in the presence of injury.

Febrile seizures increase the threshold for development of epilepsy.

Women with a higher birth weight are more likely to develop breast cancer later in life.

Birth-weight is positively associated with breast cancer.

The risk of breast cancer among parous women increases with placental weight of pregnancies, and this association is strongest for premenopausal breast cancer.

The relationship between a breast cancer patient's capacity to metabolize tamoxifen and treatment outcome is dependent on the patient's genetic make-up.

Incidence rates of cervical cancer have increased due to nationwide screening programs based primarily on cytology to detect uterine cervical cancer.

Incidence rates of cervical cancer have decreased.

Up-regulation of the p53 pathway and related molecular events casues cancer resistance and results in a significantly shortened lifespan marked by senescent cells and accelerated organismal aging.

Obesity is determined solely by environmental factors.

ALDH1 expression is associated with better breast cancer outcomes.


Hypothalamic glutamate neurotransmission is crucial to energy balance.

Febrile seizures reduce the threshold for development of epilepsy.

Integrating classroom-based collaborative learning with Web-based collaborative learning leads to subpar class performance

Inositol lipid 3-phosphatase PTEN converts Ptdlns(3,4)P 2 into phosphatidylinositol 4-phosphate.

The combination of H3K4me3 and H3K79me2 is found in quiescent hair follicle stem cells.

ADAR1 binds to Dicer to cleave pre-miRNA.

IFIT1 restricts viral replication by sequestrating mis-capped viral RNAs.

Localization of PIN1 in the roots of Arabidopsis does not require VPS9a

The PPR MDA5 has two N-terminal CARD domains.

Recurrent mutations occur frequently within CTCF anchor sites adjacent to oncogenes.

Localization of PIN1 in the Arabidopsis embryo does not require VPS9a

CR is associated with higher methylation age.

cSMAC formation enhances weak ligand signalling.

The locus rs647161 is associated with colorectal carcinoma.

The ureABIEFGH gene cluster encodes urease maturation proteins : UreD/UreH, UreE, UreF, and UreG.

The PRR MDA5 has a central DExD/H RNA helices domain.

Peroxynitrite is required for nitration of TCR/CD8.


CHEK2 is not associated with breast cancer.

The genomic aberrations found in matasteses are very similar to those found in the primary tumor.

Deletion of αvβ8 does not result in a spontaneous inflammatory phenotype.

Cells lacking clpC have a defect in sporulation efficiency in Bacillus subtilis.

Glycolysis is one of the primary glycometabolic pathways in cells.

Ly6C hi monocytes have a lower inflammatory capacity compared to their Ly6C lo counterparts.

Individuals with low serum vitamin D concentrations have increased risk of multiple sclerosis.

DMRT1 is a sex-determining gene that is epigenetically regulated by the MHM region.

Mice that lack Interferon-γ or its receptor exhibit high resistance to experimental autoimmune myocarditis.

Macrolides have no protective effect against myocardial infarction.

Albendazole is used to treat lymphatic filariasis.

ALDH1 expression is associated with poorer prognosis in breast cancer.

A deficiency of vitamin B12 increases blood levels of homocysteine.

NR5A2 is important in development of endometrial tissues.

mTORC2 regulates intracellular cysteine levels through xCT inhibition.

The risk of breast cancer among parous women increases with placental weight of pregnancies, and this association is strongest for premenopausal breast cancer.

The extracellular domain of TMEM27 is cleaved in human beta cells.

Women with a higher birth weight are more likely to develop breast cancer later in life.

Birth-weight is positively associated with breast cancer.


CR is associated with higher methylation age.

Flexible molecules experience greater steric hindrance in the tumor microenviroment than rigid molecules.

Replacement of histone H2A with H2A.Z slows gene activation in yeasts by stabilizing +1 nucleosomes.

AMP-activated protein kinase (AMPK) activation increases inflammation-related fibrosis in the lungs.

The availability of safe places to study is not effective at decreasing homelessness.

Mutant mice lacking SVCT2 have greatly increased ascorbic acid levels in both brain and adrenals.

The DdrB protein from Deinococcus radiodurans is an alternative SSB.

Lack of clpC does not affect sporulation efficiency in Bacillus subtilis cells.

NOX2-independent pathways can generate peroxynitrite by reacting with nitrogen intermediates.

Silencing of Bcl2 is important for the maintenance and progression of tumors.

The arm density of TatAd complexes is due to structural rearrangements within Class1 TatAd complexes such as the 'charge zipper mechanism'.

Low nucleosome occupancy correlates with low methylation levels across species.

ALDH1 expression is associated with better breast cancer outcomes.

Ly6C hi monocytes have a lower inflammatory capacity compared to their Ly6C lo counterparts.

Histone demethylase recruitment and a transient decrease in histone methylation is necessary for ligand-dependent induction of transcription by nuclear receptors.

The locus rs647161 is associated with colorectal carcinoma.

Ly6C hi monocytes have a lower inflammatory capacity than Ly6C lo monocytes.


CRP is not predictive of postoperative mortality following Coronary Artery Bypass Graft (CABG) surgery.

Incidence rates of cervical cancer have increased due to nationwide screening programs based primarily on cytology to detect uterine cervical cancer.

Chronic aerobic exercise alters endothelial function, improving vasodilating mechanisms mediated by NO.

Insomnia can be effectively treated with cognitive behavioral therapy.

cSMAC formation enhances weak ligand signalling.

N-terminal cleavage reduces success identifying transcription start sites.

ADAR1 binds to Dicer to cleave pre-miRNA.

Nanoparticles can be targeted against specific cell types by incorporating aptamers into lipid nanoparticles.

Hematopoietic Stem Cell purification reaches purity rate of up to 50%.

Primary cervical cancer screening with HPV detection has higher longitudinal sensitivity than conventional cytology to detect cervical intraepithelial neoplasia grade 2.

Diabetic patients with acute coronary syndrome experience increased short-term and long-term risk for bleeding events.

High levels of CRP reduces the risk of exacerbations in chronic obstructive pulmonary disease (COPD).

Dexamethasone decreases risk of postoperative bleeding.

The severity of cardiac involvement in amyloidosis can be described by the degree of transmurality of late gadolinium enhancement in MRI.

LDL cholesterol has no involvement in the development of cardiovascular disease.

Angiotensin converting enzyme inhibitors are associated with increased risk for functional renal insufficiency.

GATA-3 is important for hematopoietic stem cell (HSC) function.

The myocardial lineage develops from cardiac progenitors of mesodermal origin.

Incidence of heart failure decreased by 10% in women since 1979.


CX3CR1 on the Th2 cells impairs T cell survival

Ubiquitin ligase UBC13 generates a K63-linked polyubiquitin moiety at PCNA K164.

CHEK2 is not associated with breast cancer.

Headaches are not correlated with cognitive impairment.

1,000 genomes project enables mapping of genetic sequence variation consisting of rare variants with larger penetrance effects than common variants.

Albendazole is used to treat lymphatic filariasis.

Basophils counteract disease development in patients with systemic lupus erythematosus (SLE).

Ly49Q directs the organization of neutrophil migration to inflammation sites by regulating membrane raft functions.

Suboptimal nutrition is not predictive of chronic disease

Synaptic activity enhances local release of brain derived neurotrophic factor from postsynaptic dendrites.

CX3CR1 on the Th2 cells promotes T cell survival

Reduced responsiveness to interleukin-2 in regulatory T cells is associated with greater resistance to autoimmune diseases such as Type 1 Diabetes.

TCR/CD3 microdomains are a required to induce the immunologic synapse to activate T cells.

T regulatory cells (tTregs) lacking αvβ8 are more adept at suppressing pathogenic T-cell responses during active inflammation.

ITAM phosphorylation prevents the transfer of the T cell receptor (TCR) signal from the echo-domain to the cytoplasmic tail of the T cell receptor (TCR).

CX3CR1 on the Th2 cells suppresses airway inflammation.

CX3CR1 on the Th2 cells promotes airway inflammation.

In adult tissue, most T cells are memory T cells.

UCB T cells reduce TCR diversity after transplantation.


CX3CR1 on the Th2 cells promotes T cell survival

Peroxynitrite is required for nitration of TCR/CD8.

Proteins synthesized at the growth cone are ubiquitinated at a higher rate than proteins from the cell body.

CX3CR1 on the Th2 cells suppresses airway inflammation.

Cataract and trachoma are the primary cause of blindness in Southern Sudan.

Arterioles have a larger lumen diameter than venules.

Tumor necrosis factor alpha (TNF-α) and interleukin-1 (IL-1) are pro-inflammatory cytokines that inhibit IL-6 and IL-10.

APOE4 expression in iPSC-derived neurons increases AlphaBeta production and tau phosphorylation causing GABA neuron degeneration.

CR is associated with higher methylation age.

Leuko-increased blood increases infectious complications in red blood cell transfusion.

Autologous transplantation of mesenchymal stem cells causes fewer opportunistic infections than induction therapy with anti-interleukin-2 receptor antibodies.

UCB T cells maintain high TCR diversity after transplantation.


CX3CR1 on the Th2 cells promotes airway inflammation.

DMRT1 is a sex-determining gene that is epigenetically regulated by the MHM region.

Therapeutic use of the drug Dapsone to treat pyoderma gangrenous is based on anecdotal evidence.

The amount of publicly available DNA data doubles every 10 years.

Increased vessel density along with a reduction in fibrosis decreases the efficacy of chemotherapy treatments.

Taking 400mg of α-tocopheryl acetate helps to prevent prostate cancer.

UCB T cells maintain high TCR diversity after transplantation.

Histone demethylase recruitment and a transient decrease in histone methylation is necessary for ligand-dependent induction of transcription by nuclear receptors.

Anthrax spores can be disposed of easily after they are dispersed.

ALDH1 expression is associated with poorer prognosis in breast cancer.

Crosstalk between dendritic cells (DCs) and innate lymphoid cells (ILCs) is important in the regulation of intestinal homeostasis.

Immune responses result in the development of inflammatory Th17 cells and anti-inflammatory iTregs.

AMP-activated protein kinase (AMPK) activation increases inflammation-related fibrosis in the lungs.

Blocking the interaction between TDP-43 and respiratory complex I proteins ND3 and ND6 leads to increased TDP-43-induced neuronal loss.

Ly49Q directs the organization of neutrophil migration to inflammation sites by regulating membrane raft functions.

Ly6C hi monocytes have a lower inflammatory capacity compared to their Ly6C lo counterparts.


CX3CR1 on the Th2 cells suppresses airway inflammation.

CX3CR1 on the Th2 cells promotes airway inflammation.

cSMAC formation enhances weak ligand signalling.

All hematopoietic stem cells segregate their chromosomes randomly.

N-terminal cleavage reduces success identifying transcription start sites.

Immune responses result in the development of inflammatory Th17 cells and anti-inflammatory iTregs.

Arginine 90 in p150n is important for interaction with EB1.

High cardiopulmonary fitness causes increased mortality rate.

CX3CR1 on the Th2 cells impairs T cell survival

CX3CR1 on the Th2 cells promotes T cell survival

High levels of CRP reduces the risk of exacerbations in chronic obstructive pulmonary disease (COPD).


Carriers of the alcohol aldehyde dehydrogenase deficiency mutation drink less that non-carries.

The ureABIEFGH gene cluster encodes urease maturation proteins : UreD/UreH, UreE, UreF, and UreG.

IgA plasma cells that are specific for transglutaminase 2 accumulate in the duodenal mucosa on commencement of a gluten-free diet.

Downregulation and mislocalization of Scribble prevents cell transformation and mammary tumorigenesis.

NR5A2 is important in development of endometrial tissues.

In adult tissue, most T cells are memory T cells.

Tetraspanin-3 is a causative factor in the development of acute myelogenous leukemia

Errors in peripheral IV drug administration are most common during bolus administration and multiple-step medicine preparations.

PDPN promotes efficient motility along stromal surfaces by activating the C-type lectin receptor to rearrange the actin cytoskeleton in dendritic cells.

Histone demethylase recruitment and a transient decrease in histone methylation is necessary for ligand-dependent induction of transcription by nuclear receptors.

PD-1 triggering on monocytes reduces IL-10 production by monocytes.

HNF4A mutations can cause diabetes in mutant carriers by the age of 14 years

There is no association between HNF4A mutations and diabetes risks.

A deficiency of vitamin B12 increases blood levels of homocysteine.

Taxation of sugar-sweetened beverages had no effect on the incidence rate of type II diabetes in India.

Female carriers of the Apolipoprotein E4 (APOE4) allele have increased risk for dementia.

Vitamin D deficiency is unrelated to birth weight.

Omnivores produce less trimethylamine N-oxide from dietary I-carnitine than vegetarians.

Ethanol stress decreases the expression of IBP in bacteria.

High dietary calcium intakes are unnecessary for prevention of secondary hyperparathyroidism in subjects with 25(OH)D levels above 75 nmol/liter.


Cataract and trachoma are the primary cause of blindness in Southern Sudan.

ITAM phosphorylation prevents the transfer of the T cell receptor (TCR) signal from the echo-domain to the cytoplasmic tail of the T cell receptor (TCR).

Up-regulation of the p53 pathway and related molecular events casues cancer resistance and results in a significantly shortened lifespan marked by senescent cells and accelerated organismal aging.

NOX2-independent pathways can generate peroxynitrite by reacting with nitrogen intermediates.

Smc5/6 engagment drives the activation of SUMO E3 ligase Mms21 by ATP-dependent remolding.

Deamination of cytidine to uridine on the minus strand of viral DNA results in catastrophic G-to-A mutations in the viral genome.

Gene expression does not vary appreciably across genetically identical cells.

MicroRNA is involved in the regulation of Neural Stem Cell (NSC) differentiation and proliferation dynamic homeostasis

Asymptomatic visual impairment screening in elderly populations does not lead to improved vision.

Infection of human T-cell lymphotropic virus type 1 is most frequent in individuals of African origin.

A total of 1,000 people in the UK are asymptomatic carriers of vCJD infection.

Mathematical models predict that using Artemisinin-based combination therapy over nongametocytocidal drugs have a dramatic impact in reducing malaria transmission.

Headaches are not correlated with cognitive impairment.

Hypoglycemia increases the risk of dementia.

Human T-lymphotropic virus type-I-associated myelopathy / tropical spastic paraparesis (HAM/TSP) patients produce Immunoglobulin G (IgG) antibodies which cross-react with an immunodominant epitope in Tax.

Antiretroviral therapy reduces rates of tuberculosis across a broad range of CD4 strata.

New drugs for tuberculosis often do not penetrate the necrotic portion of a tuberculosis lesion in high concentrations.


Cell autonomous sex determination in somatic cells does not occur in Galliformes.

Articles published in open access format are more likely to be cited than traditional journals.

There is an inverse relationship between hip fractures and statin use.

Exposure to fine particulate air pollution is relate to anxiety prevalence.

High levels of copeptin decrease risk of diabetes.

Cytochrome c is released from the mitochondrial intermembrane space to cytosol during apoptosis.

Proteins synthesized at the growth cone are ubiquitinated at a higher rate than proteins from the cell body.

Rapid up-regulation and higher basal expression of interferon-induced genes increase survival of granule cell neurons that are infected by West Nile virus.

Pseudogene PTENP1 regulates the expression of PTEN by functioning as an miRNA decoy.

Cell autonomous sex determination in somatic cells occurs in Passeriformes.

Mitochondria are uninvolved in apoptosis.

In domesticated populations of Saccharomyces cerevisiae, whole chromosome aneuploidy is very uncommon.

All hematopoietic stem cells segregate their chromosomes randomly.

Gene expression does not vary appreciably across genetically identical cells.

Assembly of invadopodia is triggered by focal generation of phosphatidylinositol-3,4-biphosphate and the activation of the nonreceptor tyrosine kinase Src.

Transplanted human glial cells can differentiate within the host animal.

Replacement of histone H2A with H2A.Z slows gene activation in yeasts by stabilizing +1 nucleosomes.

Transplanted human glial progenitor cells are incapable of forming a neural network with host animals' neurons.


Cell autonomous sex determination in somatic cells occurs in Passeriformes.

Golli-deficient T-cells prefer to differentiate into an anergic phenotype in the adaptive immune response when there are increased levels of Ca2+ in the cytosol.

Monoclonal antibody targeting of N-cadherin inhibits metastasis.

Cells undergoing methionine restriction may activate miRNAs.

Inositol lipid 3-phosphatase PTEN converts Ptdlns(3,4)P 2 into phosphatidylinositol 4-phosphate.

Tumor necrosis factor alpha (TNF-α) and interleukin-1 (IL-1) are pro-inflammatory cytokines that inhibit IL-6 and IL-10.

Activation of PPM1D suppresses p53 function.

Hypoglycemia increases the risk of dementia.

The PPR MDA5 has two N-terminal CARD domains.

Obesity is determined solely by environmental factors.

The myocardial lineage develops from cardiac progenitors of mesodermal origin.


Cells lacking clpC have a defect in sporulation efficiency in Bacillus subtilis.

Ly6C hi monocytes have a lower inflammatory capacity than Ly6C lo monocytes.

Autologous transplantation of mesenchymal stem cells causes a higher rate of opportunistic infections than induction therapy with anti-interleukin-2 receptor antibodies.

There is an inverse relationship between hip fractures and statin use.

IRG1 has antiviral effects against neurotropic viruses.

Aspirin inhibits the production of PGE2.

TCR/CD3 microdomains are a required to induce the immunologic synapse to activate T cells.

Fz/PCP-dependent Pk localizes to the anterior membrane of neuroectoderm cells during zebrafish neuralation

Transplanted human glial progenitor cells are incapable of forming a neural network with host animals' neurons.

Lack of clpC does not affect sporulation efficiency in Bacillus subtilis cells.

Mutant mice lacking SVCT2 have greatly increased ascorbic acid levels in both brain and adrenals.

Ly6C hi monocytes have a lower inflammatory capacity compared to their Ly6C lo counterparts.

Proteins synthesized at the growth cone are ubiquitinated at a higher rate than proteins from the cell body.

Crossover hot spots are not found within gene promoters in Saccharomyces cerevisiae.

Increased vessel density along with a reduction in fibrosis decreases the efficacy of chemotherapy treatments.

Ethanol stress decreases the expression of IBP in bacteria.

Upregulation of mosGCTL-1 is induced upon infection with West Nile virus.


Cells undergoing methionine restriction may activate miRNAs.

Women with a higher birth weight are more likely to develop breast cancer later in life.

Smc5/6 engagment drives the activation of SUMO E3 ligase Mms21 by ATP-dependent remolding.

Febrile seizures reduce the threshold for development of epilepsy.

Deamination of cytidine to uridine on the minus strand of viral DNA results in catastrophic G-to-A mutations in the viral genome.

Downregulation and mislocalization of Scribble prevents cell transformation and mammary tumorigenesis.

Low nucleosome occupancy correlates with low methylation levels across species.

The treatment of cancer patients with co-IR blockade does not cause any adverse autoimmune events.

The severity of cardiac involvement in amyloidosis can be described by the degree of transmurality of late gadolinium enhancement in MRI.

The PRR MDA5 has a central DExD/H RNA helices domain.

High levels of CRP reduces the risk of exacerbations in chronic obstructive pulmonary disease (COPD).

Low expression of miR7a does represses target genes and exerts a biological function in ovaries.

ADAR1 binds to Dicer to cleave pre-miRNA.

Low expression of miR7a exerts a biological function in testis.

ITAM phosphorylation prevents the transfer of the T cell receptor (TCR) signal from the echo-domain to the cytoplasmic tail of the T cell receptor (TCR).

Pseudogene PTENP1 regulates the expression of PTEN by functioning as an miRNA decoy.

mTORC2 regulates intracellular cysteine levels through xCT inhibition.

IFIT1 restricts viral replication by sequestrating mis-capped viral RNAs.

N348I mutations cause resistance to zidovudine (AZT).

Mercaptopurine is anabolized into the inactive methylmercaptopurine by thiopurine methyltrasnferase (TPMT).


Cellular aging closely links to an older appearance.

Crossover hot spots are not found within gene promoters in Saccharomyces cerevisiae.

The locus rs647161 is associated with colorectal carcinoma.

The repair of Cas9-induced double strand breaks in human DNA is error-prone.

Alizarin forms hydrogen bonds with residues involved in PGAM1 substrate binding.

Most termination events in Okazaki fragments are sequence specific.

NR5A2 is important in development of endometrial tissues.

Leuko-reduced blood reduces infectious complications in red blood cell transfusion.

Cold exposure increases BAT recruitment.

Ultrasound guidance significantly raises the number of traumatic procedures when attempting needle insertion.

Women with a higher birth weight are more likely to develop breast cancer later in life.

Modifying the epigenome in the brain affects the normal human aging process by affecting certain genes related to neurogenesis.

Obesity is determined solely by environmental factors.

Up-regulation of the p53 pathway and related molecular events casues cancer resistance and results in a significantly shortened lifespan marked by senescent cells and accelerated organismal aging.

Gene expression does not vary appreciably across genetically identical cells.

Breast cancer development is determined exclusively by genetic factors.

The myocardial lineage develops from cardiac progenitors of mesodermal origin.

Macropinocytosis contributes to a cell's supply of amino acids via the intracellular uptake of protein.


Chenodeosycholic acid treatment increases whole-body energy expenditure.

GATA-3 is important for hematopoietic stem cell (HSC) function.

Cytosolic proteins bind to iron-responsive elements on mRNAs coding for DMT1. Cytosolic proteins bind to iron-responsive elements on mRNAs coding for proteins involved in iron uptake.

IgA plasma cells that are specific for transglutaminase 2 accumulate in the duodenal mucosa on commencement of a gluten-free diet.

Teaching hospitals do not provide better care than non-teaching hospitals.

Immune complex triggered cell death leads to extracellular release of neutrophil protein HMGB1.

Inositol lipid 3-phosphatase PTEN converts Ptdlns(3,4)P 2 into phosphatidylinositol 4-phosphate.

aPKCz causes tumour enhancement by affecting glutamine metabolism.

Homozygous deletion of murine Sbds gene from osterix-expressing mesenchymal stem and progenitor cells (MPCs) prevents oxidative stress.

Normal expression of RUNX1 has tumor-promoting effects.

Chenodeosycholic acid treatment reduces whole-body energy expenditure.

High dietary calcium intakes are unnecessary for prevention of secondary hyperparathyroidism in subjects with 25(OH)D levels above 75 nmol/liter.

Angiotensin converting enzyme inhibitors are associated with increased risk for functional renal insufficiency.

Sildenafil improves erectile function in men who experience sexual dysfunction as a result of the use of SSRI antidepressants.

A deficiency of vitamin B12 increases blood levels of homocysteine.

Ethanol stress decreases the expression of IBP in bacteria.

Dexamethasone decreases risk of postoperative bleeding.


Chenodeosycholic acid treatment reduces whole-body energy expenditure.

The genomic aberrations found in matasteses are very similar to those found in the primary tumor.

Arginine 90 in p150n is important for interaction with EB1.

Ribosomopathies have a low degree of cell and tissue specific pathology.

Errors in peripheral IV drug administration are most common during bolus administration and multiple-step medicine preparations.

Ivermectin is used to treat lymphatic filariasis.

Lack of clpC does not affect sporulation efficiency in Bacillus subtilis cells.

PKG-la plays an essential role in expression of pain hypersensitivity in PGK-la knockout mice.

Mutant mice lacking SVCT2 have greatly increased ascorbic acid levels in both brain and adrenals.

High levels of CRP reduces the risk of exacerbations in chronic obstructive pulmonary disease (COPD).

Hypocretin neurones induce panicprone state in rats.

NOX2-independent pathways can generate peroxynitrite by reacting with nitrogen intermediates.


Chronic aerobic exercise alters endothelial function, improving vasodilating mechanisms mediated by NO.

Cell autonomous sex determination in somatic cells does not occur in Galliformes.

Patients in stable partnerships have a faster progression from HIV to AIDS.

Hypertension is frequently observed in type 1 diabetes patients.

Ethanol stress decreases the expression of IBP in bacteria.

Cell autonomous sex determination in somatic cells occurs in Passeriformes.

FoxO3a activation in neuronal death is mediated by reactive oxygen species (ROS).

Leuko-reduced blood reduces infectious complications in red blood cell transfusion.

De novo assembly of sequence data has more specific contigs than unassembled sequence data.

Cytochrome c is released from the mitochondrial intermembrane space to cytosol during apoptosis.

Vitamin D deficiency is unrelated to birth weight.

AMP-activated protein kinase (AMPK) activation increases inflammation-related fibrosis in the lungs.

The deregulated and prolonged activation of monocytes has deleterious effects in inflammatory diseases.

CX3CR1 on the Th2 cells promotes airway inflammation.

CX3CR1 on the Th2 cells suppresses airway inflammation.

The severity of cardiac involvement in amyloidosis can be described by the degree of transmurality of late gadolinium enhancement in MRI.

Up-regulation of the p53 pathway and related molecular events casues cancer resistance and results in a significantly shortened lifespan marked by senescent cells and accelerated organismal aging.

Ly49Q directs the organization of neutrophil migration to inflammation sites by regulating membrane raft functions.

ALDH1 expression is associated with poorer prognosis in breast cancer.


Cold exposure increases BAT recruitment.

Autologous transplantation of mesenchymal stem cells causes a higher rate of opportunistic infections than induction therapy with anti-interleukin-2 receptor antibodies.

Only a minority of cells survive development after differentiation into stress-resistant spores.

The locus rs647161 is associated with colorectal carcinoma.

Venules have a thinner or absent smooth layer compared to arterioles.

Pretreatment with the Arp2/3 inhibitor CK-666 affects lamelliopodia formation.

ALDH1 expression is associated with better breast cancer outcomes.

The availability of safe places to study is effective at decreasing homelessness.

Cells undergoing methionine restriction may activate miRNAs.

ITAM phosphorylation prevents the transfer of the T cell receptor (TCR) signal from the echo-domain to the cytoplasmic tail of the T cell receptor (TCR).

Non-invasive ventilation use should be decreased if there is inadequate response to conventional treatment.

Exposure to fine particulate air pollution is relate to anxiety prevalence.

In mice, P. chabaudi parasites are able to proliferate faster early in infection when inoculated at lower numbers than when inoculated at high numbers.

High levels of copeptin decrease risk of diabetes.

Ethanol stress decreases the expression of IBP in bacteria.

New drugs for tuberculosis often do not penetrate the necrotic portion of a tuberculosis lesion in high concentrations.


Microarray results from culture-amplified mixtures of serotypes correlate poorly with microarray results from uncultured mixtures.

Febrile seizures increase the threshold for development of epilepsy.

The combination of H3K4me3 and H3K79me2 is found in quiescent hair follicle stem cells.

Headaches are not correlated with cognitive impairment.

NF2 (Merlin) causes phosphorylation and subsequent cytoplasmic sequestration of YAP in Drosophila by activating LATS1/2 kinases.

New drugs for tuberculosis often do not penetrate the necrotic portion of a tuberculosis lesion in high concentrations.

Asymptomatic visual impairment screening in elderly populations does not lead to improved vision.

Anthrax spores can be disposed of easily after they are dispersed.

Rapamycin decreases the concentration of triacylglycerols in fruit flies.

Hematopoietic Stem Cell purification reaches purity rate of up to 50%.

Antiretroviral therapy reduces rates of tuberculosis across a broad range of CD4 strata.


Combination nicotine replacement therapies with varenicline or bupropion lead to significantly higher long-term abstinence rates at 52 weeks than varenicline monotherapy.

Dexamethasone decreases risk of postoperative bleeding.

Integrating classroom-based collaborative learning with Web-based collaborative learning leads to subpar class performance

Ubiquitin ligase UBC13 generates a K63-linked polyubiquitin moiety at PCNA K164.

The tip of the inner tube of the toxic type VI secretion system (T6SS) antibacterial effector in Escherichia coli (E. coli) carries toxic effector proteins.

PGE 2 promotes intestinal tumor growth by altering the expression of tumor suppressing and DNA repair genes.

Arginine 90 in p150n is important for interaction with EB1.

Articles published in open access format are less likely to be cited than traditional journals.

N-terminal cleavage reduces success identifying transcription start sites.

Rapid phosphotransfer rates govern fidelity in two component systems

Varenicline monotherapy is more effective after 12 weeks of treatment compared to combination nicotine replacement therapies with varenicline or bupropion.

Sildenafil improves erectile function in men who experience sexual dysfunction as a result of the use of SSRI antidepressants.

High dietary calcium intakes are unnecessary for prevention of secondary hyperparathyroidism in subjects with 25(OH)D levels above 75 nmol/liter.

In young and middle-aged adults, current or remote uses of ADHD medications do not increase the risk of serious cardiovascular events.

The risk of breast cancer among parous women increases with placental weight of pregnancies, and this association is strongest for premenopausal breast cancer.

Mathematical models predict that using Artemisinin-based combination therapy over nongametocytocidal drugs have a dramatic impact in reducing malaria transmission.

Taking 400mg of α-tocopheryl acetate helps to prevent prostate cancer.