
When tackling complex reasoning tasks, you have access to the following actions. Use them as needed to progress through your thought process.

[ASSESS]

[ADVANCE]

[VERIFY]

[SIMPLIFY]

[SYNTHESIZE]

[PIVOT]

[OUTPUT]

You should strictly follow the format below:

[ACTION NAME]

# Your action step 1

# Your action step 2

# Your action step 3

...

Next action: [NEXT ACTION NAME]


system
Given a parabola $E$: $y^{2}=2px (p > 0)$ and a point $M$ $(x_{0}, 4)$ on it, the distance between $M$ and the focus $F$ is $|MF|= \frac {5}{4}x_{0}$.
(I) Find the equation of $E$;
(II) A line $l$ through $F$ intersects $E$ at points $A$ and $B$. The perpendicular bisector of $AB$, denoted as $l'$, intersects $E$ at points $C$ and $D$. If $\overrightarrow{AC} \cdot \overrightarrow{AD}=0$, find the equation of line $l$.

Present the answer in LaTex format: \boxed{Your answer}
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