Voss Creek is a stream in Franklin County in the U.S. state of Missouri. It is a tributary of the Bourbeuse River. The headwaters rise just east of Missouri Route EE (at ) and it flows to the east-southeast passing south of the community of Neier to its confluence with the Bourbeuse about east of its source (at ). The confluence with the Bourbeuse is about southwest of Union and west-northwest of St. Clair. Voss Creek most likely was named after Dietrich Voss, the proprietor of a local mill.