protocolSection identificationModule nctId: NCT06390020, orgStudyIdInfo id: NL84880.091.23, briefTitle: Mindfulness-Based Stress Reduction (MBSR) for People High on the Personality Trait Sensory Processing Sensitivity: A Mixed Methods Study, acronym: MindSens, statusModule overallStatus: RECRUITING, startDateStruct date: 2024-01-15, primaryCompletionDateStruct date: 2024-12, completionDateStruct date: 2024-12, studyFirstPostDateStruct date: 2024-04-29, lastUpdatePostDateStruct date: 2024-04-29, sponsorCollaboratorsModule leadSponsor name: Radboud University Medical Center, class: OTHER, descriptionModule briefSummary: This study investigates the efficacy of MBSR training in alleviating stress-related symptoms among individuals with high sensory processing sensitivity. Participants will be randomly allocated to either the MBSR group or the control group.The primary hypothesis is that participants in the MBSR group, relative to control group, will have lower depression-anxiety-stress scores post-intervention, after controlling for baseline scores. The secondary hypothesis is that in the MBSR group, relative to control group, other mental health, physical health and well-being outcomes, as well as potential mindfulness mechanisms will also improve, after controlling for baseline scores., conditionsModule conditions: Sensory Processing Sensitivity, designModule studyType: INTERVENTIONAL, phases: NA, designInfo allocation: RANDOMIZED, interventionModel: PARALLEL, primaryPurpose: TREATMENT, maskingInfo masking: NONE, enrollmentInfo count: 52, type: ESTIMATED, armsInterventionsModule interventions name: MBSR, outcomesModule primaryOutcomes measure: Change from Baseline to Post-intervention in self-reported depression, anxiety, and stress, secondaryOutcomes measure: Change from Baseline to Post-intervention in self-reported well-being, secondaryOutcomes measure: Change from Baseline to Post-intervention in self-reported burnout symptoms, secondaryOutcomes measure: Change from Baseline to Post-intervention in self-reported physical symptoms, secondaryOutcomes measure: Change from Baseline to Post-intervention in self-reported overstimulation, secondaryOutcomes measure: Change from Baseline to Post-intervention in self-reported mindfulness, secondaryOutcomes measure: Change from Baseline to Post-intervention in self-reported attention regulation, secondaryOutcomes measure: Change from Baseline to Post-intervention in self-reported strategies for cognitive emotion regulation, secondaryOutcomes measure: Change from Baseline to Post-intervention in self-reported body awareness, secondaryOutcomes measure: Change from Baseline to Post-intervention in self-reported self-compassion, secondaryOutcomes measure: Change from Baseline to Post-intervention in self-reported sensory processing sensitivity, secondaryOutcomes measure: Perceived facilitators, barriers, effects, and mechanisms of participating in the MBSR training, eligibilityModule sex: ALL, minimumAge: 18 Years, stdAges: ADULT, stdAges: OLDER_ADULT, contactsLocationsModule locations facility: The Radboudumc Center for Mindfulness, status: RECRUITING, city: Nijmegen, state: Gelderland, zip: 6525 GC, country: Netherlands, contacts name: Anne Speckens, prof. dr., role: CONTACT, phone: (024) 36 68 456, email: mindfulness@radboudumc.nl, geoPoint lat: 51.8425, lon: 5.85278, hasResults: False