Single alkyl phosphonate modification of the siRNA backbone in the seed region enhances specificity and therapeutic profile
Mehran Nikan, Qingfeng Li, M. Tanowitz, Hongda Li, Sagar Damle, Marie Annoual, Rodrigo Galindo-Murillo, Audrey Low, Stephanie K Klein, Clare Quirk, Guillermo Vasquez, W Brad Wan, Andrew T Watt, M. Migawa, E. Swayze, Thazha P. Prakash
Nucleic Acids Research