The BCL-2 inhibitor APG-2575 resets tumor-associated macrophages toward the M1 phenotype, promoting a favorable response to anti-PD-1 therapy via NLRP3 activation
F. Luo, Han Li, Wenjuan Ma, Jiaxin Cao, Qun Chen, Fei-Teng Lu, Miao-zhen Qiu, Penghui Zhou, Zeng-Fei Xia, Kangmei Zeng, J. Zhan, Ting Zhou, Qiuyun Luo, Wen-Tao Pan, Lin Zhang, Chaozhuo Lin, Yan Huang, Li Zhang, Dajun Yang, Hongyun Zhao
Cellular & Molecular Immunology