Question: when did assassin 's creed syndicate come out

Answer: October 23 , 2015

This is a document about Assassin's Creed Syndicate
 Assassin's Creed Syndicate Assassin's Creed Syndicate is an action-adventure video game developed by Ubisoft Quebec and published by Ubisoft. It was released on October 23, 2015, for PlayStation 4 and Xbox One, and on November 19, 2015, for Microsoft Windows. It is the ninth major installment in the "Assassin's Creed" series, and the successor to 2014's "Assassin's Creed Unity". The plot is set in a fictional history of real-world events and follows the centuries-old struggle between the Assassins, who fight for peace with liberty, and the Templars, who desire peace through order. The story is set in Victorian era London

This is a document about Assassin's Creed Syndicate
 March 1, 2016 for all platforms. The score to "Assassin's Creed Syndicate" was composed by American composer Austin Wintory. The lyrical songs in the game, murder ballads, were composed by Wintory and Australian musical comedy band, Tripod. The soundtrack was released on Amazon MP3 and iTunes on October 23, 2015. "Assassin's Creed Syndicate" received "generally favorable" reviews for the PlayStation 4 and Xbox One versions, while the PC version of the game received "mixed or average" reviews from critics, according to review aggregator Metacritic. Alexa Corriea from GameSpot praised the fluidity of "Syndicate"s new combat system, as well as the

This is a document about Assassin's Creed Syndicate
  Assassin's Creed Syndicate is an action-adventure video game developed by Ubisoft Quebec and published by Ubisoft. It was released on October 23, 2015, for PlayStation 4 and Xbox One, and on November 19, 2015, for Microsoft Windows. It is the ninth major installment in the Assassin's Creed series, and the successor to 2014's Assassin's Creed Unity. The game's plot follows the premise of the Assassin's Creed franchise, involving a fictional history of real-world events where a secret war has been fought for centuries between two factions: the Brotherhood of Assassins, who promote peace and liberty, and the Templar Order, who desire peace through control. The framing story is set in the 21st century and follows the same unnamed and unseen protagonist from Assassin's Creed Unity,

This is a document about Assassin's Creed
  Assasssin's Creed Syndicate was released in October 2015 for the PlayStation 4 and Xbox One, in November 2015 for Windows, and in December 2020 for the Stadia. In the present-day, players control the same unnamed Assassin Initiate from Assassin's Creed Unity, who this time must help the Assassins locate a powerful artifact, the Shroud of Eden, hidden somewhere in London. The main story is set in Victorian era London and follows twin assassins Jacob and Evie Frye as they navigate the corridors of organized crime, and gradually take back the city from Templar control. In December 2014, images and information leaked for a new Assassin's Creed game, titled or code-named Victory, which was later confirmed by Ubisoft. In May 2015, Kotaku leaked that Victory had been renamed Syndicate. On May 12, 2015, the game was officially announced by Ubisoft. The game retains several gameplay elements from Unity, and introduces new travelling systems, such as carriages and a grappling hook, and refined combat mechanics. It is the first game in the series to feature multiple playable protagonists, whom the player can switch between both during and outside missions.

This is a document about Ubisoft Quebec
  After developing expansion packs for Assassin's Creed III and Assassin's Creed IV: Black Flag, Ubisoft Quebec became the first Ubisoft studio outside Ubisoft Montreal to lead the development of a mainline Assassin's Creed game. The studio's first Assassin's Creed game was Assassin's Creed Syndicate, which was released in October 2015, and continued with Assassin's Creed Odyssey, released in October 2018.

This is a document about Far Cry 5
  other major titles, The Crew 2 and Assassin's Creed Origins, which were released in fiscal year 2018. Ubisoft released several teaser trailers and the game's cover art ahead of the game's official reveal on May 26, 2017. The game was released on Microsoft Windows, PlayStation 4 and Xbox One with support for PlayStation 4 Pro and Xbox One X. Free skin packs were made available for PlayStation 4 players at launch due to a marketing deal between Sony Interactive Entertainment and Ubisoft. Though the game was initially set for release on February 27, 2018, Ubisoft pushed the date back a month to March 27, 2018.

This is a document about Assassin's Creed (video game)
  Assassin's Creed is an action-adventure video game developed by Ubisoft Montreal and published by Ubisoft. It is the first installment in the Assassin's Creed series. The game was released for PlayStation 3 and Xbox 360 in November 2007. A Microsoft Windows version titled Assassin's Creed: Director's Cut Edition and containing additional content was released in April 2008. The plot is set in a fictional history of real-world events, taking place primarily during the Third Crusade in the Holy Land in 1191. The player character is a modern-day man named Desmond Miles who, through a machine called the "Animus", relives the genetic memories of his ancestor, Altaïr Ibn-La'Ahad. Through this plot device, details emerge about a millennia-old struggle between two factions: the Assassin Brotherhood (inspired by the real-life Order

This is a document about Assassin's Creed (film)
  Brotherhood during the Spanish Inquisition, to gain the skills of a Master Assassin and battle the Templar Order. Filming began in late August 2015 and concluded in January 2016. Assassin's Creed was released on December 21, 2016, in the United States and France. It generally received negative reviews from critics that were primarily aimed towards the plot and writing, though some considered it an improvement over previous video game film adaptations. The film underperformed at the box office, grossing $240 million worldwide against its $125 million budget. Due to the film's negative reception, Fox cancelled the sequel, following the acquisition of 21st Century Fox by Disney in 2019.

This is a document about Assassin's Creed Syndicate
  different aspects of London; most notably, the Jack the Ripper expansion, set twenty years after the main campaign, deals with a series of murders carried out by the titular unidentified serial killer. Assassin's Creed Syndicate received positive reviews, with praise for its visuals, characters, narrative, and level design. However, the combat, open-world design and vehicle gameplay were met with some criticism. The game was nominated for multiple awards, including Best Action/Adventure at The Game Awards 2015. Syndicate was less financially successful than previous entries in the series, selling roughly 5.5 million copies by November 2017. It was followed in October 2017 by Assassin's Creed Origins, which introduces a new storyline in the modern day and has its main plot set in Ptolemaic era Ancient Egypt.

This is a document about Assassin's Creed Origins
  incorporated an overhauled "hitbox-based" combat system. The game's development began following the release of Assassin's Creed IV: Black Flag (2013). Ubisoft Montreal led its four-year development with help from a team of nearly 700 people from other Ubisoft studios around the world. The team consulted Egyptologists and historians extensively to ensure the setting was authentically represented in the game. While Assassin's Creed had been an annual franchise since Assassin's Creed II (2009), an extra year of development time allowed the team to polish the game further. This was largely a response to the tepid sales of Syndicate, and the troubled launch of Unity, which was plagued with technical issues when it was released in 2014. Announced at E3 2017, Origins was released on

This is a document about Assassin's Creed Origins
  Following the release of Assassin's Creed Syndicate (2015), which sold fewer copies than its predecessors, Ubisoft decided against releasing an Assassin's Creed game in 2016. Ubisoft allowed one year of additional development time so they could "evolve the game mechanics" and reposition the series as a "premier open-world franchise". Ubisoft CEO Yves Guillemot later added that this also gave the Montreal studio additional time to polish the game and learn from Assassin's Creed Unity (2014), whose troubled launch alienated the series' fans. Ubisoft had released new installments in the franchise every year since 2009's Assassin's Creed II. Assassin's Creed Origins was first leaked in January 2016, with Kotaku sources suggesting the game was codenamed Empire and set in

This is a document about Syndicate (series)
  Syndicate, the first game in the series, was first released for PC and Amiga in June 1993, with later releases on other platforms including Sega Genesis, SNES, and PlayStation Portable. In 2015, the game was made available for free on Electronic Arts' Origin platform, however it now costs £4.25 (As of 20JUN19). An expansion pack, titled Syndicate: American Revolt, was also released for PC and Amiga in 1993.

This is a document about Assassin's Creed (film)
  Assassin's Creed was released on December 21, 2016. The film was originally announced in May 2013 to be released on May 22, 2015, a date that was pushed back the following month to June 26, 2015. In November 2013, the film was pushed back once again to a new release date of August 7, 2015. In September 2014, the film was pushed to an unspecified 2016 release date, which was later revealed to be December 21, 2016. The film was released in 2D, 3D and selected IMAX 3D territories.

This is a document about Assassin's Creed
  Assassin's Creed Unity was released in November 2014 (concurrently with Rogue) for the PlayStation 4, Xbox One, Windows, and Stadia. In the present-day, the player character is a player of Helix, an Animus-powered gaming device produced by Abstergo, who hope to use their unware playerbase to locate more Pieces of Eden. While playing, the player is contacted by the modern-day Assassins, and invited to join them as an Initiate and help them locate the body of an 18th-century Sage. The main story is set in Paris during the French Revolution, and follows Assassin Arno Dorian as he attempts to avenge his foster father's death at the hands of the Templars, which leads him to discover an internal conflict between the Templars as a result of the Revolution. On March 19, 2014, images leaked for the next Assassin's Creed game, titled or code-named Unity, showing a new assassin in Paris. On March 21, Ubisoft confirmed the game's existence, having been in development for more than three years, by releasing pre-alpha game footage. The game features enhanced visuals compared to its predecessors, and several new gameplay mechanics, including a four player co-op mode, a first for the series.

This is a document about Syndicate (series)
  Reports of a new Syndicate game, developed for EA by Starbreeze Studios, first surfaced in March 2009 and were officially confirmed in September 2011. The game, also entitled Syndicate, was released on 21 February 2012; however, it used a first-person shooter format, which differed significantly from the isometric real-time tactics format of the series' original games.

This is a document about Assassin's Creed Syndicate
  Assassin's Creed Syndicate is the second major entry in the series not to be developed by Ubisoft Montreal, following 2014's Assassin's Creed Rogue. Instead, on July 2, 2014, Ubisoft announced that Ubisoft Quebec would handle lead development as part of "a major investment" in the studio, who had assisted in the making of the six prior games as well as The Tyranny of King Washington and Freedom Cry, downloadable content for Assassin's Creed III and Assassin's Creed IV: Black Flag respectively. Marc-Alexis Côté serves as the creative director for the game after working in various positions on Brotherhood, Revelations, Assassin's Creed III, and Freedom Cry while

This is a document about Assassin's Creed: Brotherhood
  Assassin's Creed: Brotherhood is a 2010 action-adventure video game developed by Ubisoft Montreal and published by Ubisoft. It is the third major installment in the Assassin's Creed series, and the second chapter in the "Ezio Trilogy", as a direct sequel to 2009's Assassin's Creed II. The game was first released on the PlayStation 3 and Xbox 360 in November and December 2010 and was later made available on Microsoft Windows in March and June 2011. The plot is set in a fictional history of real-world events and follows the millennia-old struggle between the Assassins, who fight to preserve peace and free will, and the Templars, who desire peace through control. The framing story is set in the 21st century and features series protagonist Desmond Miles who, with

This is a document about Assassin's Creed Syndicate
  Assassin's Creed Syndicate debuted at number one in the UK according to Chart-Track. However, in its first week, it was the second worst-selling game of the franchise in the UK, only outselling Assassin's Creed Rogue. According to reports from Ubisoft, these lower sales in the first week were due to the release of Assassin's Creed Unity (2014) having a negative impact on the sales due to its notorious number of bugs and glitches at launch. Syndicates second week sales beat those of Unitys. The game was the ninth best-selling retail game in the UK. By February 2016, the game has sold over 4.12million units worldwide. As of November 2017, Assassin's Creed Syndicate has sold over 5.5 million copies worldwide.

This is a document about Assassin's Creed: Brotherhood
  completing his task on Brotherhood. A teaser trailer of the multiplayer mode was released on the official site before the E3. A cinematic debut trailer was diffused during Ubisoft's E3 2010 press conference along a walkthrough of the game's beginning. Assassin's Creed: Brotherhood reached gold status on October 28, 2010. The Microsoft Windows version has Nvidia 3D Vision and multi screen support through AMD Eyefinity. It also uses Tagès copy protection, as well as Ubisoft online services platform, but doesn't require an always-on Internet connection to play. On November 30, 2010, a novelization of the game was published. The novel is a sequel to the previous novel.

Assassin's Creed Syndicate was released on October 23, 2015.


Question: where is planet of the apes filmed 2017

Answer: Vancouver

This is a document about War for the Planet of the Apes
 to the fifth film in the original series, "Battle for the Planet of the Apes", but it is not a direct remake. Principal photography began on October 14, 2015, in Vancouver, British Columbia, Canada. "War for the Planet of the Apes" premiered in New York City on July 10, 2017, and was theatrically released in the United States on July 14, 2017, by 20th Century Fox. The film has grossed over $490 million and received critical praise, with many reviewers highlighting the performances (particularly Serkis's), visual effects, story, direction, and musical score. The film received a nomination for Best Special

This is a document about Coquihalla Canyon Provincial Park
 It was expanded to its current hectares in 2004. The park's rock cliffs and relatively close distance to Vancouver has resulted in many popular movies being filmed there. "First Blood", "Shoot to Kill", "", "Cabin in the Woods" and "War for the Planet of the Apes" were all filmed in Coquihalla Canyon. The location is easily recognizable when watching "First Blood" where Sylvester Stallone hangs off the cliff while a helicopter tries to snipe him down. As of May 2015, the tunnels have reopened after having been closed for over a year due to rockfall concerns. Coquihalla Canyon Provincial Park

This is a document about Planet of the Apes (2001 film)
  Burton wanted to begin filming in October 2000, but it was pushed back to November 6, 2000 and ended in April 2001. Filming for Planet of the Apes began at Lake Powell, where parts of the original film were shot. Due to a local drought, production crews had to pump in extra water. The film was mostly shot at Sony Pictures Studios in Culver City, California, while other filming locations included lava plains in Hawaii and Trona Pinnacles at Ridgecrest. To preserve secrecy, the shooting script did not include the ending. Stan Winston was the original makeup designer but left because of creative differences. Fox considered using computer-generated

This is a document about Gravity (2013 film)
  at Lake Powell, Arizona—where the astronauts' landing scene in Planet of the Apes (1968) was also filmed. Principal photography began in London, on 9 May 2011. The film contains 156 shots, with an average length of 45 seconds—fewer and longer shots than in most films of its length. Although the first trailer had audible explosions and other sounds, these scenes are silent in the finished film. Cuarón said, "They put in explosions [in the trailer]. As we know, there is no sound in space. In the film, we don't do that." The soundtrack in the film's space scenes consists of the musical score and

This is a document about Linda Harrison
  whatever. But never a peep out of her. Most pleasant, most charming, very cooperative, very hard-working. She was always there half an hour before her call and she always stayed on for a half hour just in case. Interested in everything that went on, and was a total joy. I couldn't ask for a more cooperative actor.'" Planet of the Apes commenced filming on May 21, 1967 and ended August 10, 1967. The first scenes were shot on locations near Page, Arizona. Horseshoe Bend on the Colorado River stood in for the Forbidden Zone, through which Taylor, Zira, Cornelius, and Harrison's Nova fled after escaping

This is a document about Linda Harrison
  probably a great deal of footage of it somewhere." After filming in the desert concluded, production moved to Malibu Creek State Park, northwest of Los Angeles, on Las Virgenes Road off Mulholland Highway, where the 20th Century Fox's Malibu Ranch was located. Ape City was built on the ranch, and a field of corn grown, by which Heston first encounters Harrison. "It was stinking hot," Harrison recalled. "The scenes of us in cages were also shot at Ape City." From the Malibu Ranch, production moved to the coast, where the penultimate scenes were shot between Malibu and Oxnard. The final scenes were filmed in

This is a document about Avengers: Infinity War
  in Edinburgh, Glasgow, and the Scottish Highlands, with studio work taking place at Wardpark Studios in Cumbernauld. In late June 2017, filming occurred in Downtown Atlanta, as well as Atlanta's Central Park in early July, before moving to Queens, New York in the middle of the month. Filming concluded on July 14, 2017. For the film's final scene, where Thanos settles in a nipa hut, the filmmakers worked with Thailand-based studio Indochina Productions to acquire footage of the Banaue Rice Terraces at Ifugao, Philippines. Later in July 2017, Joe Russo stated there were a couple of unfinished scenes for

This is a document about Planet of the Apes (1968 film)
  Filming began on May 21, 1967, and ended on August 10, 1967. Most of the early scenes of a desert-like terrain were shot in northern Arizona near the Grand Canyon, the Colorado River, Lake Powell, Glen Canyon  and other locations near Page, Arizona  Most scenes of the ape village, interiors and exteriors, were filmed on the Fox Ranch  in Malibu Creek State Park, northwest of Los Angeles, essentially the backlot of 20th Century Fox. The concluding beach scenes were filmed on a stretch of California seacoast between Malibu and Oxnard with cliffs that towered 130 ft above the shore. Reaching the beach on foot was virtually impossible, so cast, crew, film equipment, and even horses had

This is a document about T'Challa (Marvel Cinematic Universe)
  say too much about that world." Additionally, Makovsky felt creating T'Challa's royal look was "a bit of a challenge", avoiding African robes after learning actual African royalty are generally "educated in the West [and] get dressed in Savile Row". Boseman reprised the role in Black Panther (2018). By October 2015, Joe Robert Cole was in final negotiations to write the film's script. In January 2016, it was announced that Ryan Coogler had been hired to direct the film, and was later revealed to be co-writing the script with Cole. Filming began in January 2017 at Pinewood Studios in Atlanta, Georgia. The film

This is a document about Lee "Scratch" Perry
  Upsetters, witnessing the building of Perry's "Secret Laboratory" in Switzerland from the beginning until its destruction by fire in 2015. Shot in Switzerland, Jamaica, London, and Berlin, the movie also shows scenes from Aksum and Lalibela, Ethiopia to provide necessary background information. Over the years, Schaner collected over 100 hours of unique scenes and they both still continue the work, planning to release a sequel. In 2015, Perry worked together with Belgium-based band Pura Vida and released The Super Ape Strikes Again, which was mixed at The Last Ark Studio in Belgium using a combination of vintage gear and modern recording techniques. In September

This is a document about Black Panther (film)
  Principal photography had begun by January 21, 2017, at EUE/Screen Gems Studios in the Atlanta metropolitan area, under the working title Motherland. Filming also took place at Pinewood Atlanta Studios, and in the Sweet Auburn neighborhood in Atlanta, which doubled as Oakland; the High Museum of Art, which served as the fictional Museum of Great Britain in London; and Atlanta City Hall, which served as a United Nations building. Cinematographer Rachel Morrison, who was eager to work on Black Panther after working with Coogler on Fruitvale Station, first watched all of the other MCU films to understand the established "language". She wanted to "push" that language and feature more contrast in color. Visual effects supervisor Geoff Baumann

This is a document about Planet of the Apes (TV series)
  II (1973) and favor proposals for a Planet of the Apes television series. Fox and CBS then continued Jacob's plans of a series the next year. CBS ordered 14 episodes of Planet of the Apes to be produced. The series was filmed for the most part on location at what is now Malibu Creek State Park, with a budget of about $250,000 for each episode. Originally scheduled to be broadcast during CBS's Tuesday night family hour, the first regular episode of the series was broadcast on Friday, September 13, 1974 from 8:00-9:00 PM. The remainder of the series was broadcast during this same time slot until December 27, 1974, when its 14th and final broadcast was shown as a result of a premature cancellation of the series due to poor ratings.

This is a document about Phoenix Wilder and the Great Elephant Adventure
  Principal photography took place in South Africa at a reserve in Bela Bela during the month of May in 2017. Boddington had the entire cast and crew stay in a remote location, so that no elephants would need to be transported for the production.

This is a document about Mad Max: Fury Road
  Principal photography began in July 2012 in Namibia, with most of the filming based in the Dorob National Park. Filming also took place at the Cape Town Film Studios in Cape Town, South Africa. In October 2012, The Hollywood Reporter reported that Warner Bros. sent an executive to keep the production on track. Filming wrapped on 8 December 2012, without any of the opening or closing scenes at the Citadel shot. In February 2013, a leaked draft from the Namibian Coast Conservation and Management Project accused the producers of damaging parts of the Namib desert, endangering a number of plant and animal species. The Namibia Film Commission said it had "no reservations" after visiting the set during production. It

This is a document about War for the Planet of the Apes
  the original series, Battle for the Planet of the Apes (1973), but it is not a direct remake. War for the Planet of the Apes premiered in New York City on July 10, 2017, and was theatrically released in the United States on July 14, 2017, by 20th Century Fox. The film was a commercial success having grossed over $490 million. It received critical acclaim, with many reviewers highlighting the performances (particularly Serkis'), visual effects, story, direction, cinematography, musical score and emotional depth. The film received a nomination for Best Special Visual Effects at the 71st British Academy Film Awards, and was nominated for Best Visual Effects at the 90th Academy Awards. It was also nominated for four Saturn Awards, including Best Director for Reeves and Best Actor for Serkis.

This is a document about Hobbs & Shaw
  Principal photography began on September 10, 2018, in London, England. Dwayne Johnson joined the production two weeks later, on September 24, 2018, after he had wrapped filming Jungle Cruise. Most filming was done at Shepperton Studios and Leavesden Studios. In October, filming moved to Glasgow, Scotland, to recreate London. Filming also took place in late 2018 at Eggborough power station in North Yorkshire, and in Farnborough, Hampshire. The Hawaiian island of Kaua'i was used as a stand-in for Samoa for the film's third act. Cinematographer Jonathan Sela shot the film with Arri Alexa SXT and Alexa Mini digital cameras and Hawk Class-X anamorphic lenses. Production officially wrapped on January 27, 2019. Scroggins Aviation Mockup & Effects was hired to supply a UH-60 Black Hawk (s/n 79-23354) in the film. Scroggins made modification to the UH-60 and worked with the art department to supply it with a digital cockpit panel.

This is a document about Cosmic Birth
  The interviews with the astronauts were conducted from 2013 to 2019 in Iceland as well as in the United States. Most of the astronauts appearing in the film are interviewed both on location in the Apollo geology training areas in Iceland and in space museums and at their homes in the United States. Filming in Iceland took place in 2013, 2015 and 2017 during the Apollo astronauts' revisits to their geology training areas. Filming in the US took place in 2018 and 2019 at the Stafford Air & Space Museum in Weatherford, Oklahoma, at the San Diego Air & Space Museum in San Diego, California, at Cape Canaveral and Kennedy Space Center in Florida, and at the American Museum of Natural History and the Explorers Club in New York.

This is a document about Transformers: Age of Extinction
  the Planet of the Apes in its fifth weekend. International openings of over $5 million occurred in South Korea ($21.7 million), Brazil ($16.5 million), Germany ($11.2 million), Australia ($9.6 million), France ($8.8 million), Taiwan ($8.1 million), Malaysia ($6.7 million), Japan ($6.4 million), the Philippines ($5.7 million), India ($5.35 million), Hong Kong ($5.1 million), and Italy ($5 million). In Russia, the film opened to number one with $21.7 million from 1,100 screens, which is the second-largest in the territory for which 3D accounted for 80% of the total gross. IMAX comprised $2.6 million of the total gross from 34 IMAX screens. Its biggest

This is a document about Planet of the Apes (1968 film)
  be lowered in by helicopter. The remains of the Statue of Liberty were shot in a secluded cove on the far eastern end of Westward Beach, between Zuma Beach and Point Dume in Malibu. As noted in the documentary Behind the Planet of the Apes, the special effect shot of the half-buried statue was achieved by seamlessly blending a matte painting with existing cliffs. The shot looking down at Taylor was done from a 70 ft scaffold, angled over a 1⁄2-scale papier-mache model of the Statue. The actors in Planet of the Apes were so affected by their roles and wardrobe that, when not shooting, they automatically segregated themselves with the species they were portraying.

The 2017 film "War for the Planet of the Apes" was primarily filmed in Vancouver, British Columbia, Canada. Some scenes were also filmed at Coquihalla Canyon Provincial Park in British Columbia.


Question: who 's the actress that plays abby on ncis

Answer: Pauley Perrette

This is a document about Pauley Perrette
 Pauley Perrette Pauley Perrette (born March 27, 1969) is an American actress, best known for playing Abby Sciuto on the U.S. TV series "NCIS". She is also a published writer, singer, and civil rights advocate. Perrette was born in New Orleans and raised throughout the southern United States. On "The Late Late Show with Craig Ferguson", she told host Craig Ferguson that she lived in Georgia, Alabama, Tennessee, North Carolina, South Carolina, New York, New Jersey, and California. In a 2011 interview with the Associated Press, Perrette confessed her early ambitions were to work with animals, be in a rock

This is a document about NCIS (season 15)
 when Bello's character premieres. In another central casting announcement, "TV Line" reported on October 4, 2017, that founding NCIS actress Pauley Perrette will be leaving the role of "Abby Sciuto" after the conclusion of season fifteen. Perrette's final episode was episode 22, which aired on May 8, 2018. Also, in this episode, Duane Henry (Clayton Reeves) was written off the show. NCIS was renewed for a sixteenth season on April 13, 2018, following a deal with Mark Harmon to return for an additional two years. <onlyinclude> </onlyinclude> Season 15 was praised for its sharp cases and bringing new life into

This is a document about NCIS (soundtrack)
 "NCIS" stars Pauley Perrette ("Abby Sciuto"), who performs the self-composed "Fear" under the moniker Stop Making Friends, and Cote de Pablo ("Ziva David"), whose memorable performance of Tom Waits' "Temptation" from the Season 6 premiere episode, "Last Man Standing," is included. It is Perrette’s character, Abby, whose music sensibilities in the show serve as the basis for the soundtrack’s "Abby’s Lab" disk 2. NCIS: The Official TV Soundtrack – Vol. 2 is the second soundtrack album from the television series "NCIS". The album is a 12-track set that includes brand new and exclusive songs from artists featured prominently in 2009-2010

This is a document about Abby Sciuto
 Abby Sciuto Abigail "Abby" Sciuto is a fictional character from the "NCIS" television series on CBS Television, and is portrayed by Pauley Perrette. In a season 10 episode entitled "Hit and Run", a young Abby was played by Brighton Sharbino in flashbacks. Like Jethro Gibbs, Anthony DiNozzo, and Dr. Donald Mallard, Abby was introduced in the episodes "Ice Queen" and "Meltdown" of the television show "JAG" (which together served as the backdoor pilot for "NCIS"), and, up until May 2018, appeared in every episode of "NCIS," in addition to being featured on the show's spin-offs, "" (two episodes) and ""

This is a document about Abby Sciuto
 is meant to be Italian-American. Abby Sciuto Abigail "Abby" Sciuto is a fictional character from the "NCIS" television series on CBS Television, and is portrayed by Pauley Perrette. In a season 10 episode entitled "Hit and Run", a young Abby was played by Brighton Sharbino in flashbacks. Like Jethro Gibbs, Anthony DiNozzo, and Dr. Donald Mallard, Abby was introduced in the episodes "Ice Queen" and "Meltdown" of the television show "JAG" (which together served as the backdoor pilot for "NCIS"), and, up until May 2018, appeared in every episode of "NCIS," in addition to being featured on the show's spin-offs,

This is a document about NCIS: New Orleans (season 2)
 a second season, that premiered on September 22, 2015. On June 19, 2015, Daryl Mitchell and Shalita Grant, who had been recurring cast members, were promoted to series regulars. Mark Harmon, Pauley Perrette, David McCallum, Emily Wickersham, and Brian Dietzen guest starred as Leroy Jethro Gibbs, Abby Sciuto, , Ellie Bishop, and Jimmy Palmer respectively in the 12th episode of the season. <onlyinclude></onlyinclude> General NCIS: New Orleans (season 2) The second season of "" premiered on CBS on September 22, 2015. The season airs following "NCIS", on Tuesdays at 9:00 pm (ET). The second season of the "NCIS: New Orleans"

This is a document about Hit and Run (NCIS)
 present, Gibbs gives Abby the fortune she had given him after their first case together, which reads "Today's new friend is tomorrow's family". "Hit and Run" is written by Gary Glasberg and Gina Lucita Monreal and directed by Dennis Smith. "It all started with a photo – Pauley Perrette as a little girl", Monreal said about how Glasberg "knew the story of little Abby on her first case could be magic". Instead of looking back at "her first days of working at NCIS" Glasberg was more interested in "When did Abby first start develop an interest in forensics? And in

This is a document about Gay Men's Chorus of Los Angeles
 musical performances and a question and answer period. The GMCLA is supported by the "Foresters Financial Voice Awards." This annual award show is running on its 6th consecutive year and it aims to honor those who use their platforms for social change and advancement towards equality. In 2016, the award show raised funds in support of GCMLA's outreach programs: the "Alive Music Project" and the "it gets better Tour." Hosted by Ross Mathews, television host from the popular show Hollywood Today Live, and Pauley Perrette, actress most commonly known for her role as Abby Sciuto in NCIS, the show was

This is a document about NCIS (TV series)
 pilot of "". "Legend" introduces Chris O'Donnell as G. Callen, LL Cool J as Sam Hanna, Daniela Ruah as Kensi Blye, and Barrett Foa as Eric Beale. Rocky Carroll recurs on "NCIS: Los Angeles" as his "NCIS" character Director Leon Vance, while Pauley Perrette has appeared twice as Abby, and Michael Weatherly has appeared once as Anthony DiNozzo. "NCIS" guest stars reprising roles between series include David Dayan Fisher as CIA Officer Trent Kort, in the season-one finale of "NCIS: Los Angeles"; Kelly Hu as Lee Wuan Kai in "NCIS: Los Angeles" and later in an episode of "NCIS". John

This is a document about NCIS (TV series)
 her role as Special Agent Lara Macy. Linda Hunt and Adam Jamal Craig were confirmed to replace her in starring roles, playing OSP Manager Henrietta Lange and Special Agent Dom Vail respectively. Craig, who left the series in episode 21 of season 1, was replaced by Eric Christian Olsen playing Marty Deeks. Characters from "NCIS" have appeared in the spin-off. Rocky Carroll portrayed Leon Vance in a recurring role, while Pauley Perrette portrayed Abby Sciuto and appeared in the season 1 episodes "Killshot" and "". "NCIS: Los Angeles" was created by Shane Brennan. In April 2011, "NCIS" creator Donald Bellisario

This is a document about Shabbat Shalom (NCIS)
 a common greeting used in Israel on the Jewish Sabbath. Several characters in the episode — Ziva and Eli David, Jackie and Leon Vance — are shown observing the Shabbat shortly before the fatal shootout at the end. "NCIS" follows a team of government agents who work for the Naval Criminal Investigative Service. The main cast includes Mark Harmon as team leader Leroy Jethro Gibbs, Michael Weatherly as Senior Agent Anthony "Tony" DiNozzo, Cote de Pablo as Mossad Liaison Officer turned NCIS Agent Ziva David, Pauley Perrette as Forensic Specialist Abby Sciuto, Sean Murray as Special Agent Timothy McGee, David

This is a document about Hiatus (NCIS)
 (Michael Weatherly) or Abby (Pauley Perrette) would depart with the conclusion of Part II, saying, "We assume CBS would never be stupid enough to kill off series star Mark Harmon, who plays hard-nosed Leroy Gibbs, who is already suffering memory loss after a recent explosion." Jae-Ha Kim of Amazon.com later described the events of the finale as "explosive" in her review of the third season. Michelle Calbert from BuddyTV included the "Hiatus" two-part in her list of "The 10 Best Gibbs Episodes" and wrote, "We're including both episodes as one because they are basically just one two-hour episode. Gibbs is

This is a document about Berlin (NCIS)
 producers advertised the reported development of Ziva's relationship with Tony within the episode. Particularly, a scene in which the characters dance together while in Berlin was heavily promoted and received favorable commentary from reviewers. "NCIS" follows a team of government agents who work for the Naval Criminal Investigative Service. The main cast includes Mark Harmon as team leader Leroy Jethro Gibbs, Michael Weatherly as Senior Agent Anthony "Tony" DiNozzo, Cote de Pablo as Mossad Liaison Officer turned NCIS Agent Ziva David, Pauley Perrette as Forensic Specialist Abby Sciuto, Sean Murray as Special Agent Timothy McGee, David McCallum as Autopsy Technician

This is a document about Truth or Consequences (NCIS)
 was fascinating and sort of unreal, but all ended up well in the end. Then again, we know there's got to be no way that NCIS will split this team up - although I did have a scary moment there when Abby (Pauley Perrette) said she felt that Ziva was no longer in their universe." Sarah Lafferty from Starpulse.com noted, "Vengeance has always been the fuel for team Gibbs as well as a strong unrelenting theme of the show." Lafferty added, "'NCIS' season premieres NEVER disappoint. Even if it all goes down in only the last 15 minutes of the

This is a document about Recovery (NCIS)
 he wants the building back to its original standards as he wants to go back in time and prevent the attack, believing he is responsible for the attack. "Recovery" is written by Scott Williams and directed by Dennis Smith. "Our agents recover a co-worker who’s been missing since our season finale bombing. But they also begin recovering from the loss of any true sense of security", Williams say about the characters in the episode. Pauley Perrette, who portrays Abby, told "TV Line" that "Abby is the sensitive one — she feels the most pain and worries about everyone — so

This is a document about I Get That a Lot
 working the front desk at a hotel, Tim Gunn taking orders at a fast food restaurant, Nick Jonas working at Forever 21, Wynonna Judd selling tires, Jay Mohr as a coffee house employee and Martha Stewart as a craft store employee. Sherman Hemsley made an appearance in Brady's segment as the individual pranked by Brady. The fourth episode aired on CBS January 4, 2012 at 8:00 p.m., starring "NCIS"' s Pauley Perrette (in her Abby Sciuto attire) as a dog groomer, Ty Pennington of "" as a hardware store clerk, Olympic medalist Apolo Ohno as a produce worker, talk personality

This is a document about NCIS: Los Angeles (season 1)
 series regular the following episode. Rocky Carroll had a recurring role as Leon Vance, the Director of NCIS. Brian Avers appeared in three episodes as Special Agent ; Pauley Perrette appeared in two episodes as Abby Sciuto, the forensic specialist at NCIS headquarters. Eric Christian Olsen guest starred in two episodes as , the NCIS / LAPD Liaison Officer. <onlyinclude></onlyinclude> The series premiere episode, "", drew approximately 18.73 million viewers with a 4.4/11 share in the 18- to 49-year-old demographic and therefore won its timeslot. It was the second most watched show of the week, behind the seventh season premiere

This is a document about Hiatus (NCIS)
 Harmon) being severely injured in a ship bombing, his subsequent memory loss, and the team's struggle to find the perpetrator before another attack. The episodes also delve into Gibbs' past, culminating in the revelation of his wife and daughter's deaths 15 years prior. "NCIS" follows a team of government agents who work for the Naval Criminal Investigative Service. The main cast during the filming of the third season included Mark Harmon as team leader Leroy Jethro Gibbs, Michael Weatherly as Senior Agent Anthony "Tony" DiNozzo, Cote de Pablo as Mossad Liaison Officer Ziva David, Pauley Perrette as Forensic Specialist Abby

This is a document about NCIS (TV series)
 as Tony, Robyn Lively as Vivian Blackadder, Pauley Perrette as Abby, and David McCallum as Ducky. Patrick Labyorteaux appears on "NCIS" reprising his "JAG" role as Lt. Bud Roberts in the first-season episode "Hung Out to Dry", and in the fourteenth-season episode "Rogue"; Alicia Coppola returned as Lt. Cmdr. Faith Coleman in "UnSEALed", "Call of Silence", and "Hometown Hero", while Adam Baldwin returned as Cmdr. Michael Rainer in "A Weak Link", and John M. Jackson appeared as retired Rear Admiral A. J. Chegwidden in the season-ten episode "Damned If You Do". The two-part "NCIS" episode "Legend" serves as the back-door

Pauley Perrette plays the role of Abby on NCIS.


Question: who sang the original version of last kiss

Answer: Wayne Cochran

This is a document about Last Kiss
 Last Kiss "Last Kiss" is a song released by Wayne Cochran in 1961 on the Gala label. It failed to do well on the charts. Cochran subsequently re-recorded his song for the King label in 1963. It was later revived by J. Frank Wilson and the Cavaliers, Pearl Jam and several international artists, including the Canadian group Wednesday, with varying degrees of success. The song was one of several teen tragedy songs from that period. The song's opening lyrics mirror the opening lyrics of Septimus Winner's "Der Deitcher's Dog". The narrator borrows his father's car to take his beloved sweetheart

This is a document about Romance (David Cassidy album)
  Romance is David Cassidy's seventh studio album as a solo artist and his first released by Arista Records. Released in 1985, Romance was the only studio album Cassidy released during the 1980s. Since growing out of his teen idol fame from The Partridge Family, Cassidy continued to try to re-invent his music career; however, in the United States, his latter albums from the 1970s did not chart. Therefore, for the album Romance, Arista excluded a U.S. release and released the album only in Europe, Israel, Japan, South Africa and Australia. Romance peaked at no. 20 on the UK Albums Chart in June 1985. George Michael sang on the song, "The Last Kiss" (originally recorded with different lyrics by Cliff Richard in 1981 as "Young

This is a document about Last Kiss
  In 1973, "Last Kiss" was covered by the Canadian group Wednesday. Their version reached number two in Canada and number 34 in the United States. It is ranked as the 27th biggest Canadian hit of 1973. Their version climbed up the charts very slowly, and spent three weeks longer on the American charts than the Cavaliers' much bigger hit. As a result of the popularity of Wednesday's rendition, the Cavaliers' version was re-released (Virgo 506) at the end of 1973. It reached number 92 in January 1974, spending a total of five weeks on the Billboard Hot 100. The original hit version re-charted five weeks after the version by Wednesday entered the charts.

This is a document about David Cassidy
  Cassidy later stated he was broke by the 1980s, despite being successful and highly paid. In 1985, music success continued with the Arista release of the single "The Last Kiss" (number six in the United Kingdom), with backing vocals by George Michael, which was included on the album Romance. These went gold in Europe and Australia, and Cassidy supported them with a sellout tour of the United Kingdom, which resulted in the Greatest Hits Live compilation of 1986. Michael cited Cassidy as a major career influence and interviewed Cassidy for David Litchfield's Ritz Newspaper. Cassidy performed in musical theater. In 1981, he toured in a revival of a pre-Broadway production of Little

This is a document about Pearl Jam
  Ticketmaster had proven to be unsuccessful and hindered live tours. Many fans had complained about the difficulty in obtaining tickets and the use of non-Ticketmaster venues, which were judged to be out-of-the-way and impersonal. For this tour and future tours, Pearl Jam once again began using Ticketmaster in order to "better accommodate concertgoers." The 1998 summer tour was a big success, and after it was completed the band released Live on Two Legs, a live album which featured select performances from the tour. In 1998, Pearl Jam recorded "Last Kiss", a cover of a 1960s ballad made famous by J. Frank

This is a document about J. Frank Wilson and the Cavaliers
  The Cavaliers formed around 1955 with leader and guitarist Sid Holmes, bassist Lewis Elliott, saxophonist Rob Zeller, drummer Ray Smith and vocalist Alton Baird. Baird was drafted shortly after the group formed and the band brought in J. Frank Wilson, after his discharge from Goodfellow Air Force Base (San Angelo, Texas) and Sid Holmes's subsequent mental deterioration in 1962. Sonley Roush became the manager of the group. He brought to them a song originally recorded by Wayne Cochran named "Last Kiss". Duly recorded by the group, it was first released on Le Cam (722) and then on Tamara (761), before it became a hit in June 1964 on Josie Records (Josie 923). It reached

This is a document about Last Kiss
  By Wayne Cochran, Joe Carpenter, Randall Hoyal & Bobby McGlon (1961) In the summer of 1961, four friends traveled to the University of Georgia in Athens, Georgia, to record a song Wayne Cochran had written, with Joe Carpenter, Randall Hoyal and Bobby McGlon, called "Last Kiss". Wayne Cochran (vocals), Joe Carpenter (guitar), Bobby Rakestraw (bass), and Jerry Reppert (drums) recorded the song for the Gala label, a small label based in Vidalia. When the labels for the 45s, Gala #117, were printed, the names of co-writers Joe Carpenter, Randall Hoyal and Bobby McGlon were left off. Cochran evidently never asked Gala to change the label, to include the other

This is a document about Wired for Sound
  but earned gold certification from the BPI for sales over half a million. The track was recorded live at the Hammersmith Odeon on 1 May 1981, for a rock 'n' roll special to be broadcast later by BBC Television. "Broken Doll" is a cover of a Wreckless Eric single from 1980. Reportedly, Richard also wanted to record Eric's "(I'd Go The) Whole Wide World" too, but only if he could change some of the lyrics - which Eric refused. "Young Love" was given new lyrics and retitled "The Last Kiss" for a cover version by David Cassidy featuring George Michael. It was released as the lead single for Cassidy's 1985 album Romance, becoming a top ten

This is a document about Eddie Vedder
  cut down to just one line: make music." The band subsequently released No Code in 1996 and Yield in 1998. In 1998, prior to Pearl Jam's U.S. Yield Tour, Irons left the band due to dissatisfaction with touring. Pearl Jam enlisted former Soundgarden drummer Matt Cameron as Irons' replacement on an initially temporary basis, but he soon became the permanent replacement for Irons. "Do the Evolution" (from Yield) received a Grammy nomination for Best Hard Rock Performance. In 1998, Pearl Jam recorded "Last Kiss", a cover of a 1960s ballad made famous by J. Frank Wilson and the Cavaliers. It was

This is a document about Last Kiss
  the Barranquilla Carnival. Mexican singer-songwriter Gloria Trevi released her version of the song in 1989, peaking at number 36 on the Billboard Hot Latin Songs chart. During the late 1970s, "Last Kiss" was covered by the Asparagus Valley Cultural Society and was also sometimes performed as the encore to their show. In 2011, Trent Dabbs recorded a cover of "Last Kiss" for the hit television series The Vampire Diaries in Season 2, episode 18: "The Last Dance". Meadow Ryann covered this on her debut cover album, Wings. Cœur de Pirate covered the song for the soundtrack of the 2014 season of the Canadian TV show, Trauma.

This is a document about Theme Time Radio Hour
 1) "The Shoop Shoop Song (It's in His Kiss)" - Betty Everett (1964) ; 2) "Always Late with Your Kisses" - Lefty Frizzell (1951) ; 3) "Passionate Kisses" - Lucinda Williams (1988) ; 4) "Kissing At Midnight" - Billy Boy Arnold (1957) ; 5) "Kiss" - Prince (1986) ; 6) "Kissing in the Dark" - Memphis Minnie (1953) ; 7) "Kiss Tomorrow Goodbye" - Danny White (1963) ; 8) "Pucker Paint" - Huelyn Duvall (1960) ; 9) "Lipstick on Your Collar" - Connie Francis (1959) ; 10) "(Till) I Kissed You" - The Everly Brothers (1959) ; 11) "Let’s Kiss and Make Up" - The Falcons (1963) ; 12) "Baby, Let Me Kiss You One More

This is a document about Last Kiss
  "Last Kiss" came to the attention of record promoter Sonley Roush, a Texas promoter eking out a living, looking for the next big thing. Roush brought the song to a group that he booked around West Texas, the Cavaliers of San Angelo, with the proviso that singer J. Frank Wilson was still with the band. Wilson joined the Cavaliers after his discharge from Goodfellow Air Force Base (San Angelo, Texas) in 1962, but had left for a while, unsure of the future. Credit should be given also to Sid Holmes of San Angelo for founding the original Cavaliers band in c.1956. He later

This is a document about The Everly Brothers
  The Everlys, as noted above, wrote and composed "Till I Kissed You" (Don), "When Will I Be Loved" (Phil), "Born Yesterday" (Don), and "Cathy's Clown" (Don, or possibly Don and Phil). The authorship of "Cathy's Clown" has been the subject of a 2017 lawsuit and has been differently adjudicated by different courts, most recently in 2021. "Cathy's Clown" and "When Will I Be Loved" became hits for Reba McEntire and Linda Ronstadt, respectively. "Cathy's Clown" was also covered by the Tarney/Spencer Band and released as a single in 1979. Band member Alan Tarney (a former member of the Shadows) went

This is a document about Last Kiss
  "Last Kiss" is a song released by Wayne Cochran in 1961 on the Gala label. It failed to do well on the charts. Cochran subsequently re-recorded his song for the King label in 1963. It was later revived by J. Frank Wilson and the Cavaliers, Pearl Jam and several international artists, including the Canadian group Wednesday, with varying degrees of success. The song was one of several teen tragedy songs from that period. The song's opening lyrics mirror the opening lyrics of Septimus Winner's "Der Deitcher's Dog".

This is a document about Alan Tarney
  Need Someone New" by the Lotus Eaters (1983, No. 53) ; "The Love Parade" by the Dream Academy (1985, No. 68, US No. 40) ; "The Last Kiss" by David Cassidy (1985, No. 6) ; "Take On Me" by a-ha (1985, No. 2) ; "The Sun Always Shines on TV" by a-ha (1985, No. 1) ; "Train of Thought" by a-ha (1986, No. 8) ; "Hunting High and Low" by a-ha (1986, No. 5) ; "I've Been Losing You" by a-ha (1986, No. 8) ; "Cry Wolf" by a-ha (1986, No. 5) ; "Manhattan Skyline" by a-ha (1987, No. 13) ; "My Pretty One" by Cliff Richard (1987, No. 6) ; "Some People"

This is a document about Last Kiss
  to this day Cochran is the only one credited with writing "Last Kiss". Cochran would go on to re-record the song for release on Aire Records (1962), in a slightly different tempo, with some changes to the lyrics and for re-release on King Records in 1963. In all, Cochran recorded four versions of the song, the original, Gala #117, Boblo Records #101, King Records #5856, and Aire Records #150, released as "Last Kiss" b/w "Edge of the Sea", with Cochran sharing vocals with an unnamed male vocalist. The Aire disc was easily the most different version of all, with heavy reverb and a staccato drumbeat. Aire Records, located in

This is a document about Last Kiss
  The idea to cover "Last Kiss" came about after vocalist Eddie Vedder found an old record of the song at the Fremont Antique Mall in Seattle, Washington. He convinced the rest of the band to try out the song and it was performed a few times on the band's 1998 tour. The band eventually recorded the song at a soundcheck at the Merriweather Post Pavilion in Columbia, Maryland in September of that year and released it as a 1998 fan club Christmas single. The band spent only a couple of thousand dollars mixing the song. Bassist Jeff Ament said, "It was the most minimalist recording we've ever done."

This is a document about Pearl Jam
  and the Cavaliers. It was recorded during a soundcheck and released on the band's 1998 fan club Christmas single. The following year, the cover was put into heavy rotation across the country. By popular demand, the cover was released to the public as a single in 1999, with all of the proceeds going to the aid of refugees of the Kosovo War. The band also decided to include the song on the 1999 charity compilation album, No Boundaries: A Benefit for the Kosovar Refugees. "Last Kiss" peaked at number two on the Billboard charts and became the band's highest-charting single.

This is a document about Clear Channel memorandum
  Guns N' Roses). In some cases, only certain versions of songs were included on the list. For example, the cover of "Smooth Criminal" by Alien Ant Farm is on the list while the original Michael Jackson recording is not. Similarly, J. Frank Wilson's version of "Last Kiss" is included, but Pearl Jam's cover is not. Also, Martha and the Vandellas's original version of "Dancing in the Street" and Van Halen's version are included; David Bowie and Mick Jagger's recording was excluded from the list. Also, the song "Leaving on a Jet Plane" by Peter, Paul, and Mary is included, but the version by the song's composer John Denver is not.

This is a document about Last Kiss
  New Zealand. It also reached number one in Iceland, staying at the summit for six weeks. Christopher John Farley of Time said, "It's a spare, morose song with Vedder's voice warbling lovelorn over a straight-ahead drum beat. Going back to basics has put Pearl Jam back on top." Regarding the cover, guitarist Stone Gossard said, "You can try album after album to write a hit and spend months getting drum sounds and rewriting lyrics, or you can go to a used record store and pick out a single and fall in love with it." Pearl Jam included "Last Kiss" on the 2003 B-sides and rarities album, Lost Dogs, and on the 2004 greatest hits album, rearviewmirror (Greatest Hits 1991–2003).

Wayne Cochran sang the original version of "Last Kiss."


Question: which type of cell forms the blood brain barrier

Answer: endothelial cells

This is a document about Blood–brain barrier
 Blood–brain barrier The blood–brain barrier (BBB) is a highly selective semipermeable border that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS). The blood–brain barrier is formed by endothelial cells of the capillary wall, astrocyte end-feet ensheathing the capillary, and pericytes embedded in the capillary basement membrane. This system allows the passage of water, some gases, and lipid-soluble molecules by passive diffusion, as well as the selective transport of molecules such as glucose and amino acids that are crucial to neural function. Specialized structures participating in sensory and secretory integration within neural circuits

This is a document about Neuroinflammation
 later stages of inflammation. The blood–brain barrier is a structure composed of endothelial cells and astrocytes that forms a barrier between the brain and circulating blood. Physiologically, this enables the brain to be protected from potentially toxic molecules and cells in the blood. Astrocytes form tight junctions and therefore may strictly regulate what may pass the blood–brain barrier and enter the interstitial space. After injury and sustained release of inflammatory factors such as chemokines, the blood–brain barrier may be compromised, becoming permeable to circulating blood components and peripheral immune cells. Cells involved in the innate and adaptive immune responses, such

This is a document about Drug delivery to the brain
 that they must pass through the cell membranes of the endothelial cells. Because of this, the only molecules that are easily able to transverse the blood–brain barrier are ones that are very lipid-soluble. These are not the only molecules that can transverse the blood–brain barrier; glucose, oxygen and carbon dioxide are not lipid-soluble but are actively transported across the barrier, to support normal cellular function of the brain. The fact that molecules have to fully transverse the endothelial cells makes them a perfect barricade to unspecified particles from entering the brain, working to protect the brain at all costs. Also,

This is a document about Blood–brain barrier
 of the blood–brain barrier. The weakening of the blood–brain barrier may be a result of a disturbance in the endothelial cells on the inside of the blood vessel, due to which the production of the protein P-glycoprotein is not working well. There are currently active investigations into treatments for a compromised blood–brain barrier. It is believed that oxidative stress plays an important role into the breakdown of the barrier. Anti-oxidants such as lipoic acid may be able to stabilize a weakening blood–brain barrier. Neuromyelitis optica, also known as Devic's disease, is similar to and is often confused with multiple sclerosis.

This is a document about Pathophysiology of Parkinson's disease
 cells can release factors to increase the activation of M1 microglia, leading to a positive feedback loop which causes continually increasing cell death. The fifth proposed major mechanism for cell death is the breakdown of the blood-brain barrier (BBB). The BBB has three cell types which tightly regulate the flow of molecules in and out of the brain: endothelial cells, pericytes, and astrocytes. In neurodegenerative diseases, BBB breakdown has been measured and identified in specific regions of the brain, including the substantia nigra in Parkinson's disease and hippocampus in Alzheimer's disease. Protein aggregates or cytokines from neuroinflammation may interfere with

This is a document about Blood–brain barrier
 – the circumventricular organs and choroid plexus – do not have a blood–brain barrier. The blood–brain barrier restricts the diffusion of solutes in the blood (e.g., bacteria) and large or hydrophilic molecules into the cerebrospinal fluid (CSF), while allowing the diffusion of hydrophobic molecules (O, CO, hormones) and small polar molecules. Cells of the barrier actively transport metabolic products such as glucose across the barrier using specific transport proteins. This "barrier" results from the selectivity of the tight junctions between endothelial cells in CNS vessels, which restricts the passage of solutes. At the interface between blood and the brain, endothelial

This is a document about Blood–brain barrier
 cells are stitched together by these tight junctions, which are composed of smaller subunits, frequently biochemical dimers, that are transmembrane proteins such as occludin, claudins, junctional adhesion molecule (JAM), or ESAM, for example. Each of these transmembrane proteins is anchored into the endothelial cells by another protein complex that includes ZO-1 and associated proteins. The blood–brain barrier is composed of high-density cells restricting passage of substances from the bloodstream much more than do the endothelial cells in capillaries elsewhere in the body. Astrocyte cell projections called astrocytic feet (also known as "glia limitans") surround the endothelial cells of the BBB,

This is a document about Blood–brain barrier
 the two. At that time, it was thought that the blood vessels themselves were responsible for the barrier, since no obvious membrane could be found. The concept of the blood–brain barrier (then termed hematoencephalic barrier) was proposed by a Berlin physician, Lewandowsky, in 1900. Blood–brain barrier The blood–brain barrier (BBB) is a highly selective semipermeable border that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS). The blood–brain barrier is formed by endothelial cells of the capillary wall, astrocyte end-feet ensheathing the capillary, and pericytes embedded in the capillary basement membrane. This system

This is a document about Viral meningitis
 white blood cell binding and extravasation. The barrier that the meninges create between the brain and the bloodstream are what normally protect the brain from the body's immune system. Damage to the meninges and endothelial cells increases cytotoxic reactive oxygen species production, which damages pathogens as well as nearby cells. In meningitis, the barrier is disrupted, so once viruses have entered the brain, they are isolated from the immune system and can spread. This leads to elevated intracranial pressure, cerebral edema, meningeal irritation, and neuronal death. The diagnosis of viral meningitis is made by clinical history, physical exam, and several

This is a document about Meningeal syphilis
 general paresis and tabes dorsalis), and optic atrophy. Meningitis inflames and breaks down any protective membrane and cells surrounding the brain, spinal cord, and other parts of the nervous system. Bacterial meningitis is normally caused by a bacterial infection that enters the bloodstream and enters the blood-brain barrier. The blood-brain barrier consists of tight junctions. These tight junctions help to enclose endothelial cells that line the brain capillaries. Only certain water-soluble substances can move across the blood-brain barrier, while lipid-soluble substances can easily move across the blood-brain barrier. However, when any form of bacteria gets through to the blood-brain barrier,

This is a document about Pericyte
 the clearance and phagocytosis of cellular debris, and the permeability of the blood–brain barrier. Pericytes stabilize and monitor the maturation of endothelial cells by means of direct communication between the cell membrane as well as through paracrine signaling. A deficiency of pericytes in the central nervous system can cause the blood–brain barrier to break down. In the central nervous system, pericytes wrap around the endothelial cells that line the inside of the capillary. These two types of cells can be easily distinguished from one another based on the presence of the prominent round nucleus of the pericyte compared to the

This is a document about Head and neck anatomy
 (BBB) is semi-permeable membrane that controls the capillary leak potential of the circulatory system. In most parts of the body, the smallest blood vessels, called capillaries, are lined with endothelial cells, which have small spaces between each individual cell so substances can move readily between the inside and the outside of the capillary. This is not in the case of brain. In the brain, the endothelial cells fit tightly together to create a tight junction and substances cannot pass out of the bloodstream. Specialized glial cells called astrocytes form a tight junction or protective barrier around brain blood vessels and

This is a document about Paracytophagy
 "Listeria" access to the CNS by the latter two mechanisms. In peripheral tissues, "Listeria" can invade cells such as monocytes and dendritic cells from infected endothelial cells via the paracytophagous mode of invasion. Using these phagocytic cells as vectors, "Listeria" travels throughout the nerves and reaches tissues usually inaccessible to other bacterial pathogens. Similar to the mechanism seen in HIV, infected leukocytes in the blood cross the blood brain barrier and transport "Listeria" into the CNS. Once in the CNS, cell to cell spreading causes associated damage leading to brain encephalitis and bacterial meningitis. "Listeria" uses phagocytic leukocytes as a

This is a document about Drug delivery to the brain
 would be required. For this to be effective there must be a mechanism for the removal of the active form of the drug from the brain tissue. These are drug compounds that increase the permeability of the blood–brain barrier. By decreasing the restrictiveness of the barrier, it is much easier to get a molecule to pass through it. These drugs increase the permeability of the blood–brain barrier temporarily by increasing the osmotic pressure in the blood which loosens the tight junctions between the endothelial cells. By loosening the tight junctions normal injection of drugs through an [IV] can take place

This is a document about Glia limitans
 blood vessels within the brain is called the perivascularis. The main role of the glia limitans is to act as a physical barrier against unwanted cells or molecules attempting to enter the CNS. The glia limitans compartmentalizes the brain to insulate the parenchyma from the vascular and subarachnoid compartments. Within the brain, the glial limiting membrane is an important constituent of the blood–brain barrier. Experiments using electron-dense markers have discovered that functional components of the blood–brain barrier are the endothelial cells that compose the vessel itself. These endothelial cells contain highly impermeable tight junctions that cause the blood vessels of

This is a document about Neuroinflammation
  The blood–brain barrier is a structure composed of endothelial cells and astrocytes that forms a barrier between the brain and circulating blood. Physiologically, this enables the brain to be protected from potentially toxic molecules and cells in the blood. Astrocytes form tight junctions, and therefore may strictly regulate what may pass the blood–brain barrier and enter the interstitial space. After injury and sustained release of inflammatory factors such as chemokines, the blood–brain barrier may be compromised, becoming permeable to circulating blood components and peripheral immune cells. Cells involved in the innate and adaptive immune responses, such as macrophages, T cells, and B cells, may then enter into the brain. This exacerbates the inflammatory environment of the brain and contributes to chronic neuroinflammation and neurodegeneration.

This is a document about Blood–brain barrier
  The blood–brain barrier (BBB) is a highly selective semipermeable border of endothelial cells that prevents solutes in the circulating blood from non-selectively crossing into the extracellular fluid of the central nervous system where neurons reside. The blood–brain barrier is formed by endothelial cells of the capillary wall, astrocyte end-feet ensheathing the capillary, and pericytes embedded in the capillary basement membrane. This system allows the passage of some small molecules by passive diffusion, as well as the selective and active transport of various nutrients, ions, organic anions, and macromolecules such as glucose and amino acids that are crucial to neural function. The blood–brain barrier restricts the

This is a document about Drug delivery to the brain
  The blood–brain barrier is formed by special tight junctions between endothelial cells lining brain blood vessels. Blood vessels of all tissues contain this monolayer of endothelial cells, however only brain endothelial cells have tight junctions preventing passive diffusion of most substances into the brain tissue. The structure of these tight junctions was first determined in the 1960s by Tom Reese, Morris Kranovsky and Milton Brightman. Furthermore, astrocytic "end feet", the terminal regions of the astrocytic processes, surround the outside of brain capillary endothelial cells".   The astrocytes are glial cells restricted to the brain and spinal cord and help maintain blood-brain barrier properties in brain endothelial cells.

This is a document about Meningitis
  cell membrane are identified by the immune cells of the brain (astrocytes and microglia), they respond by releasing large amounts of cytokines, hormone-like mediators that recruit other immune cells and stimulate other tissues to participate in an immune response. The blood–brain barrier becomes more permeable, leading to "vasogenic" cerebral edema (swelling of the brain due to fluid leakage from blood vessels). Large numbers of white blood cells enter the CSF, causing inflammation of the meninges and leading to "interstitial" edema (swelling due to fluid between the cells). In addition, the walls of the blood vessels themselves become inflamed (cerebral vasculitis), which leads to decreased

The blood-brain barrier is formed by the endothelial cells of the capillary wall, astrocyte end-feet, and pericytes.


Question: the form of chronic inflammatory bowel disease affecting the ileum and / or colon is

Answer: Inflammatory bowel disease

This is a document about Inflammatory bowel disease
 Inflammatory bowel disease Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine. Crohn's disease and ulcerative colitis are the principal types of inflammatory bowel disease. Crohn's disease affects the small intestine and large intestine, as well as the mouth, esophagus, stomach and the anus, whereas ulcerative colitis primarily affects the colon and the rectum. In spite of Crohn's and UC being very different diseases, both may present with any of the following symptoms: abdominal pain, diarrhea, rectal bleeding, severe internal cramps/muscle spasms in the region of the pelvis and weight loss. Anemia is

This is a document about Human digestive system
 disease is a common chronic inflammatory bowel disease (IBD), which can affect any part of the GI tract, but it mostly starts in the terminal ileum. Ulcerative colitis an ulcerative form of colitis, is the other major inflammatory bowel disease which is restricted to the colon and rectum. Both of these IBDs can give an increased risk of the development of colorectal cancer. Ulcerative coliltis is the most common of the IBDs Irritable bowel syndrome (IBS) is the most common of the functional gastrointestinal disorders. These are idiopathic disorders that the Rome process has helped to define. Giardiasis is a

This is a document about Mouse model of colorectal and intestinal cancer
 of mice. Human inflammatory bowel disease is a group of inflammatory conditions in the large and small intestine. It is well known that chronic inflammation in the colon can lead to cancer. There are genetic mouse models for inflammatory bowel disease associated colon cancer. Interleukin 10 knock out mice develop invasive adenocarcinoma in the colon. Mutant mice for interleukin 2 and beta microglobulin genes also produce ulcerative colitis-like phenotype and develop adenocarcinomas in the colon. A mouse mutant for N-cadherin suffers inflammatory bowel disease conditions and adenomas but does not develop carcinomas. Humans with high levels of the diet-related bile

This is a document about Collagenous colitis
 Collagenous colitis Collagenous colitis is an inflammatory bowel disease affecting the colon specifically with peak incidence in the 5th decade of life, affecting women more than men. Its clinical presentation involves watery diarrhea in the absence of rectal bleeding. It is often classified under the umbrella entity microscopic colitis, that it shares with a related condition, lymphocytic colitis. Microscopic colitis causes chronic watery diarrhea with greater than 10 bowel movements per day. Some patients report nocturnal diarrhea, abdominal pain, urgency, fecal incontinence, fatigue, dehydration and weight loss. Patients report a significantly diminished quality of life. The cause of collagenous colitis

This is a document about Constipation
 colon, irritable bowel syndrome, and pelvic floor disorders. Underlying associated diseases include hypothyroidism, diabetes, Parkinson's disease, celiac disease, non-celiac gluten sensitivity, colon cancer, diverticulitis, and inflammatory bowel disease. Medications associated with constipation include opioids, certain antacids, calcium channel blockers, and anticholinergics. Of those taking opioids about 90% develop constipation. Constipation is more concerning when there is weight loss or anemia, blood is present in the stool, there is a history of inflammatory bowel disease or colon cancer in a person's family, or it is of new onset in someone who is older. Treatment of constipation depends on the underlying cause

This is a document about Toxic megacolon
 diarrhea, or painful bowel movements. Colonoscopy is contraindicated, as it may rupture the dilated colon resulting in peritonitis and septic shock. Toxic megacolon Toxic megacolon ("megacolon toxicum") is an acute form of colonic distension. It is characterized by a very dilated colon (megacolon), accompanied by abdominal distension (bloating), and sometimes fever, abdominal pain, or shock. Toxic megacolon is usually a complication of inflammatory bowel disease, such as ulcerative colitis and, more rarely, Crohn's disease, and of some infections of the colon, including "Clostridium difficile" infections, which have led to pseudomembranous colitis. Other forms of megacolon exist and can be congenital

This is a document about Crohn's disease
 allows access to only the colon and lower portions of the small intestines; introduction of the capsule endoscopy aids in endoscopic diagnosis. Giant (multinucleate) cells, a common finding in the lesions of Crohn's disease, are less common in the lesions of lichen nitidus. Crohn's disease is one type of inflammatory bowel disease (IBD). It typically manifests in the gastrointestinal tract and can be categorized by the specific tract region affected. A disease of both the ileum (the last part of the small intestine that connects to the large intestine), and the large intestine, Ileocolic Crohn's accounts for fifty percent of

This is a document about Pancolitis
 chronic nature of most cases of pancolitis, patients have a higher chance of developing colon cancer. Pancolitis is a kind of inflammatory bowel disease (IBD) that affects the entire internal lining of the colon. The precise causes of this inflammatory disorder are unclear, although physicians currently believe that autoimmune diseases and genetic predispositions might play a role in its progress. Genes that are known to put individuals at risk for Crohn’s disease have been shown to also increase risk of other IBD including pancolitis. Furthermore, an individual may also develop pancolitis if ulcerative colitis of only a small portion of

This is a document about Bowel infarction
 ischemia are generally separated into acute and chronic processes, because this helps determine treatment and prognosis. Bowel obstruction is most often caused by intestinal adhesions, which frequently form after abdominal surgeries, or by chronic infections such as diverticulitis, hepatitis, and inflammatory bowel disease. The condition may be difficult to diagnose, as the symptoms may resemble those of other bowel disorders. Bowel volvulus describes a specific form of bowel obstruction, where the intestine and/or mesentery are twisted, resulting in ischemia. An infarcted or dead intestinal segment is a serious medical problem because of the fact that intestines contain non-sterile contents within

This is a document about Food intolerance
 delayed by up to 48 hours. Food intolerance can present with symptoms affecting the skin, respiratory tract, gastrointestinal tract (GIT) either individually or in combination. On the skin may include skin rashes, urticaria (hives), angioedema, dermatitis, and eczema. Respiratory tract symptoms can include nasal congestion, sinusitis, pharyngeal irritations, asthma and an unproductive cough. GIT symptoms include mouth ulcers, abdominal cramp, nausea, gas, intermittent diarrhea, constipation, irritable bowel syndrome (IBS), and may include anaphylaxis. Food intolerance has been found associated with irritable bowel syndrome and inflammatory bowel disease, chronic constipation, chronic hepatitis C infection, eczema, NSAID intolerance, respiratory complaints, including asthma,

This is a document about Iron-deficiency anemia
 worms cause both inflammation and chronic blood loss by binding to a human's small-intestinal mucosa, and through their means of feeding and degradation, they can ultimately cause iron-deficiency anemia. Red blood cells contain iron, so blood loss also leads to a loss of iron. There are several causes of blood loss including menstrual bleeding, gastrointestinal bleeding, stomach ulcers, and bleeding disorders. The bleeding may occur quickly or slowly. Slow, chronic blood loss within the body — such as from a peptic ulcer, angiodysplasia, inflammatory bowel disease, a colon polyp or gastrointestinal cancer (e.g., colon cancer)— can cause iron-deficiency anemia. Menstrual

This is a document about Inflammatory bowel disease
 Broad Institute, Amgen and Massachusetts General Hospital formed with the intention to "collect and analyze patient DNA samples to identify and further validate genetic targets." In 2015, a meta-analysis on 938 IBD patients and 953 controls, IBD was significantly associated with having higher odds of vitamin D deficiency. Gram-positive bacteria present in the lumen could be associated with extending the time of relapse for ulcerative colitis. Inflammatory bowel disease Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine. Crohn's disease and ulcerative colitis are the principal types of inflammatory bowel disease. Crohn's disease

This is a document about Colorectal cancer
 obesity, smoking, and lack of physical activity. Dietary factors that increase the risk include red meat, processed meat, and alcohol. Another risk factor is inflammatory bowel disease, which includes Crohn's disease and ulcerative colitis. Some of the inherited genetic disorders that can cause colorectal cancer include familial adenomatous polyposis and hereditary non-polyposis colon cancer; however, these represent less than 5% of cases. It typically starts as a benign tumor, often in the form of a polyp, which over time becomes cancerous. Bowel cancer may be diagnosed by obtaining a sample of the colon during a sigmoidoscopy or colonoscopy. This is

This is a document about Colorectal cancer
 "Streptococcus bovis/gallolyticus" antigens or the antigens themselves in the bloodstream may act as markers for the carcinogenesis in the colon. People with inflammatory bowel disease (ulcerative colitis and Crohn's disease) are at increased risk of colon cancer. The risk increases the longer a person has the disease, and the worse the severity of inflammation. In these high risk groups, both prevention with aspirin and regular colonoscopies are recommended. Endoscopic surveillance in this high-risk population may reduce the development of colorectal cancer through early diagnosis and may also reduce the chances of dying from colon cancer. People with inflammatory bowel disease

This is a document about NDUFA13
 induced cell death. This form of apoptotic activity is inhibited by interaction with viral IRF1. GRIM-19 prevents the transactivation of signal-transducer and activator of transcription 3 (STAT3) target genes but not other STAT family members. The homologous protein to NDUFA13, GRIM-19, may play a role in Chron's disease (CD), an inflammatory bowel disease (IBD) characterized by chronic inflammation of the intestinal epithelium. Its expression is decreased in the inflamed mucosa of patients with these diseases. Nucleotide-binding oligomerization domain-containing protein 2 (NOD2), also known as caspase recruitment domain-containing protein 15 (CARD15) or inflammatory bowel disease protein 1 (IBD1), functions as a

This is a document about Gastrointestinal pathology
 biopsies have misclassified disease characteristics, 15% of colon polyps are misdiagnosed, and up to 50% of all cases of chronic inflammatory bowel disease are misdiagnosed or misclassified. Though pathology diagnosis is a critical determinant of future cancer risk and screening interval, many of these diagnoses do not result in significant morbidity or mortality for patients; thus, errors may be "masked" by the limited effect to the patient in the present context. The economic cost of inaccurate pathology diagnoses can be measured from the perspective of the healthcare system, the gastroenterologist practice and the patient. Within the healthcare system, gastroenterology pathology

This is a document about Toxic megacolon
 Toxic megacolon Toxic megacolon ("megacolon toxicum") is an acute form of colonic distension. It is characterized by a very dilated colon (megacolon), accompanied by abdominal distension (bloating), and sometimes fever, abdominal pain, or shock. Toxic megacolon is usually a complication of inflammatory bowel disease, such as ulcerative colitis and, more rarely, Crohn's disease, and of some infections of the colon, including "Clostridium difficile" infections, which have led to pseudomembranous colitis. Other forms of megacolon exist and can be congenital (present since birth, such as Hirschsprung's disease). It can also be caused by "Entamoeba histolytica" and "Shigella". It may also be

This is a document about Gastrointestinal tract
 the stomach and small intestine. These can include those organisms that cause foodborne illnesses. Gastroenteritis is the most common disease of the GI tract. Diverticular disease is a condition that is very common in older people in industrialized countries. It usually affects the large intestine but has been known to affect the small intestine as well. Diverticulosis occurs when pouches form on the intestinal wall. Once the pouches become inflamed it is known as diverticulitis. Inflammatory bowel disease is an inflammatory condition affecting the bowel walls, and includes the subtypes Crohn's disease and ulcerative colitis. While Crohn's can affect the

The form of chronic inflammatory bowel disease affecting the ileum and/or colon is called ulcerative colitis or Crohn's disease.


Question: who played bloody mary in south pacific movie

Answer: Juanita Hall

This is a document about South Pacific (1958 film)
 South Pacific (1958 film) South Pacific is a 1958 American romantic musical film based on the Rodgers and Hammerstein musical "South Pacific", which in turn is based on James A. Michener's short-story collection "Tales of the South Pacific". The film, directed by Joshua Logan, stars Rossano Brazzi, Mitzi Gaynor, John Kerr and Ray Walston in the leading roles with Juanita Hall as Bloody Mary, the part that she had played in the original stage production. The film was nominated for three Academy Awards, winning the Academy Award for Best Sound for Fred Hynes. Note: The film opens with an orchestral

This is a document about Bloody Mary (South Pacific)
 Bloody Mary (South Pacific) Bloody Mary is a character in the book "Tales of the South Pacific" by James Michener (written in 1946), which was made into the musical "South Pacific" by Rodgers and Hammerstein, and later into a film in 1958. The Bloody Mary character is Vietnamese (Tonkinese). Tonkin is the northern most province of what is now Vietnam. She was brought to the island by a French planter. She is often cast as black (most famously by Juanita Hall, who originated the character on the stage, and later portrayed her in the 1958 film), Asian or Pacific Islander.

This is a document about Bloody Mary (South Pacific)
 age of 102. Bloody Mary (South Pacific) Bloody Mary is a character in the book "Tales of the South Pacific" by James Michener (written in 1946), which was made into the musical "South Pacific" by Rodgers and Hammerstein, and later into a film in 1958. The Bloody Mary character is Vietnamese (Tonkinese). Tonkin is the northern most province of what is now Vietnam. She was brought to the island by a French planter. She is often cast as black (most famously by Juanita Hall, who originated the character on the stage, and later portrayed her in the 1958 film), Asian

This is a document about Flower Drum Song
 Juanita Hall, a light-skinned African American who had played a Tonkinese (Vietnamese) woman, Bloody Mary, in "South Pacific". Another African-American performer, Diahann Carroll, was considered for the cast but not hired. Rodgers later wrote, "what was important was that the actors gave the illusion of being Chinese. This demonstrates one of the most wonderful things about theatre audiences. People want to believe what they see on a stage, and they will gladly go along with whatever is done to achieve the desired effect. Ask them to accept Ezio Pinza as a Frenchman <nowiki>[</nowiki>in "South Pacific"<nowiki>]</nowiki>, Yul Brynner as Siamese and

This is a document about Porgy and Bess (film)
 would "do the part to the best of my ability - under the circumstances." Mezzo Muriel Smith, co-creator (double-cast with soprano Muriel Rahn) of the Broadway title role in Oscar Hammerstein's "Carmen Jones," creator of the role of Bloody Mary in the original London cast of Rodgers and Hammerstein's "South Pacific," whose more important movie ghost-singing assignments included dubbing for Zsa Zsa Gabor in John Huston's original film version of "Moulin Rouge" and for Juanita Hall in 1958's "South Pacific," turned down Samuel Goldwyn's offer to portray Bess, responding, the work ". . Doesn't do right by my people." This

This is a document about South Pacific (musical)
 roles. Myron McCormick was cast as Billis; according to Logan, no one else was seriously considered. The two roles which gave the most trouble were those of Cable and Bloody Mary. They tried to get Harold Keel for the role of Cable (he had played Curly in the West End production of "Oklahoma!") only to find that he had signed a contract with MGM under the name Howard Keel. William Tabbert was eventually cast as Cable, though Logan instructed him to lose . African-American singer Juanita Hall was cast as Bloody Mary; Logan recalled that at her audition, she took

This is a document about South Pacific (1958 film)
 I starts. Juanita Hall sang in the stage production and took part in the recording of the stage production cast album. However, she had her singing dubbed for the film version by Muriel Smith, who played Bloody Mary in the London stage production. Metropolitan Opera star Giorgio Tozzi provided the singing voice for the role of Emile de Becque in the film. John Kerr starred as 2nd Lt. Joseph Cable, USMC and his singing voice was dubbed by Bill Lee. Ken Clark, who played Stewpot, was dubbed by Thurl Ravenscroft (who sang "You're a Mean One, Mr. Grinch" and was

This is a document about Flower Drum Song (film)
 Umeki, and Juanita Hall (an African American actress who previously played the Pacific Islander Bloody Mary in the Broadway and film productions of Rodgers and Hammerstein's "South Pacific"). Anna May Wong had been scheduled to play the part of Madam Liang, but she died in February 1961, before production began. Kwan won the role of Linda Low when she met Ross Hunter, the producer of "Flower Drum Song", at a party after he saw her film debut in the 1960 film adaptation of "The World of Suzie Wong". Kwan's casting was announced in February 1961. Among various changes for the

This is a document about Bloody Mary (South Pacific)
 She trades with the US sailors who are stationed on nearby islands during the Second World War. She is learning English, and is proud that she will eventually "speak English as good as any crummy Marine". When the American spurns her daughter's hand out of prejudice, her most famous line is "Stingy bastard!" Juanita Hall won the Tony Award for Best Featured Actress in a Musical for originating this role on stage. A song from the Rodgers and Hammerstein musical about her makes U.S. Navy sailors sing, "Bloody Mary is the girl I love", "her skin is tender as DiMaggio's

This is a document about Juanita Hall
 soap opera "The Story Of Ruby Valentine" on the National Negro Network. The serial was broadcast on 35 stations, and sponsors of the broadcast included Philip Morris and Pet Milk. In 1958, she recorded "Juanita Hall Sings the Blues" (at Beltone Studios in New York City), backed by an astonishing group of jazz musicians including Claude Hopkins, Coleman Hawkins, Buster Bailey, Doc Cheatham, and George Duvivier. In 1958 she reprised Bloody Mary in the film version of "South Pacific", for which her singing part was dubbed, at Richard Rodgers's request, by Muriel Smith, who had played the role in the

This is a document about Ray Walston
 Yankees" opposite Gwen Verdon as his sexy aide Lola. The chemistry between the two was such that they both garnered critical success and won awards for their roles. After a decade in New York theater, he won a Tony Award. He starred as Luther Billis in the 1951 London production of "South Pacific". He reprised that role in the 1958 film adaptation. He and Juanita Hall (as Bloody Mary) were the only cast members to appear in both the stage and movie versions. Additional Broadway credits included "The Front Page", "Summer and Smoke", "King Richard III", "Wish You Were Here",

This is a document about France Nuyen
 was discovered on the beach by "Life" photographer Philippe Halsman. She was featured on the cover of 6 October 1958 issue of "Life". She became a motion picture actress in 1958. In her first role, she played Liat, daughter of "Bloody Mary" (played by Juanita Hall) in the Rodgers and Hammerstein musical "South Pacific". Later that year, she was cast in the lead role of the Broadway play "The World of Suzie Wong", opposite William Shatner. She was originally cast to star in the film adaptation of "The World of Suzie Wong", but was replaced by Nancy Kwan. She worked

This is a document about Odette Myrtil
 production of Harold Arlen and Johnny Mercer's "Saratoga" in 1960. She spent several years in the early 1950s portraying Bloody Mary in the original run of Rodgers and Hammerstein's "South Pacific", having succeeded Juanita Hall in the role. After 1935, her career shifted towards film, although she never left her stage roots. She had a fairly prolific career as a film actress, appearing in mainly mid-sized roles in a total of 25 films from 1936 to 1952. Previously, she only appeared as a dancer in the 1923 film "Squibs M.P." Her first speaking role was as Renée De Penable in

This is a document about Juanita Hall
 Juanita Hall Juanita Hall (née Long, November 6, 1901 – February 28, 1968) was an American musical theatre and film actress. She is remembered for her roles in the original stage and screen versions of the Rodgers and Hammerstein musicals "South Pacific" as Bloody Mary – a role that garnered her the Tony Award – and "Flower Drum Song" as Madame Liang. Born in Keyport, New Jersey, Hall received classical training at the Juilliard School. In the early 1930s, she was a special soloist and assistant director for the Hall Johnson Choir. A leading black Broadway performer in her day,

This is a document about Odette Myrtil
  of appearances on Broadway, with her last show being the original production of Harold Arlen and Johnny Mercer's Saratoga in 1960. She spent several years in the early 1950s portraying Bloody Mary in the original run of Rodgers and Hammerstein's South Pacific, having succeeded Juanita Hall in the role. After 1935, her career shifted towards film, although she never left her stage roots. She had a fairly prolific career as a film actress, appearing in mainly mid-sized roles in a total of 25 films from 1936 to 1952. Previously, she only appeared as a dancer in the 1923 film

This is a document about Flower Drum Song
  Juanita Hall, a light-skinned African American who had played a Tonkinese (Vietnamese) woman, Bloody Mary, in South Pacific. Another African-American performer, Diahann Carroll, was considered for the cast but not hired. Rodgers later wrote, "what was important was that the actors gave the illusion of being Chinese. This demonstrates one of the most wonderful things about theatre audiences.  People want to believe what they see on a stage, and they will gladly go along with whatever is done to achieve the desired effect.  Ask them to accept Ezio Pinza as a Frenchman  in South Pacific, Yul Brynner as Siamese and they are prepared to meet

This is a document about Bloody Mary (South Pacific)
  Bloody Mary is a character in the 1946 book Tales of the South Pacific by James Michener, which was made into the 1949 musical South Pacific by Rodgers and Hammerstein, and later into a film in 1958. The Bloody Mary character is Vietnamese (Tonkinese). Tonkin is the northernmost region of what is now Vietnam. She was brought to the island by a French planter. She is often cast as black (most famously by Juanita Hall, who originated the character on the stage, and later portrayed her in the 1958 film), Asian or Pacific Islander. She trades with the US sailors who are stationed on nearby islands during the Second World War. She is learning English, and is proud that she will eventually "speak English as good as any crummy Marine". When the American spurns her daughter's hand out of prejudice, her most famous line is "Stingy bastard!" Juanita

This is a document about Bloody Mary (South Pacific)
  won the Tony Award for Best Featured Actress in a Musical for originating this role on stage. A song from the Rodgers and Hammerstein musical about her makes U.S. Navy sailors sing, "Bloody Mary is the girl I love", "her skin is tender as DiMaggio's glove", and that she chews "betel nuts", and doesn't use "Pepsodent", with the refrain "Now ain't that too damn bad!" Possible models for her are Aggie Grey or her sister Mary Croudace (Auntie Mary); hotelkeepers in Apia, Samoa who hosted American film stars and military personnel. They were daughters of an Englishman and his Samoan wife. A 2001 article in Islands Magazine states that Michener renamed Aoba Island Bali-ha'i. The author interviewed the proprietor of a resort on Espiritu Santo, who claimed the "real Bloody Mary" lived on Espiritu Santo for many years after the war and lived to the age of 102.

This is a document about Joanna Ampil
  in the new documentary "The Show Must Go On" directed and produced by Sammi Cannold. The documentary film will premiere at Broadway’s Majestic Theatre on August 9, 2021 to benefit The Actor's Fund. Summer of 2021, Joanna made her Chichester Festival Theatre debut in Rogers and Hammerstein's South Pacific as Bloody Mary. The reimagined production directed by Daniel Evans paved way for re-orchestrations, introduction of a prologue, additional music from the film, and re-characterisation of Bloody Mary and her daughter Liat to fix racial overtones and eliminate ethnic stereotypes. The production starred Julian Ovenden as Emile De Becque, Gina Beck as Ensign Nellie Forbush, Rob Houchen as Lieutenant Cable, Keir Charles as Billis and Sera Maehara as Liat.

Juanita Hall played Bloody Mary in the South Pacific movie.